A.Giaccari1 · G. Gliozzo1 · G. Ciccarelli1 · G. Di Giuseppe1 · C. Castellano2 · S. Cum3 · L. Delle Monache4,13 · M. Gallo5 ·M.Lastretti6 · G. Medea7 · M. Monesi8 · R. Napoli9 · B. Pintaudi10 · E. Succurro11 · G. Turchetti
Received: 9 January 2026 / Accepted: 17 March 2026 © The Author(s) 2026
Abstract
Background and aims Although continuous glucose monitoring (CGM) devices are now standard of care among Type 1 diabetes patients, they are still relatively underutilized in Type 2 diabetes (T2D), particularly in those patients not treated with insulin. Widespread adoption continues to be hindered by a combination of factors. Chief among these is the scarcity of long-term, large-scale clinical trials demonstrating the benefits of the use of CGM in T2D. This meta-analysis aimed to address this gap by comparing CGM with self-blood glucose monitoring (SBMG), with primary outcomes of HbA1c and time in range (TIR) in insulin-treated and non-insulin-treated TD2 patients.
Methods and results Following the stringent rules mandated by our National Health Service (which requires a panel com-posed of all stakeholders involved in diabetes treatment, and includes PICO, GRADE, AGREE, and meta-analyses), we performed a systematic review of RCTs that enrolled two groups of individuals with T2D, those treated with insulin (includ-ing basal and basal-bolus regimens), and those receiving treatments other than insulin. All included trials compared CGM with structured blood glucose monitoring (SBGM) with glycated hemoglobin (HbA1c) as the main endpoint. Based on the strength and consistency of the evidence, the panel issued a strong recommendation in favor of CGM for individuals with T2D treated with insulin (including those on basal insulin alone) and for individuals with T2D not treated with insulin, par-ticularly for those with glycated hemoglobin levels≥7%. From a pharmacoeconomic perspective, outcomes were positive in both patient groups.
Conclusion CGM represents a clinically effective and cost-efficient approach to optimizing glycemic control in T2D, becom-ing mandatory among individuals on insulin therapy. Our findings support a shift in clinical practice toward the more widespread use of CGM in T2D, with regulatory frameworks and reimbursement policies needing to adapt accordingly.
Keywords CGM · Type 2 Diabetes · Metanalysis · PICO · GRADE · Guidelines
Communicated by Massimo Federici, M.D.
A. Giaccari 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。
1 Center for Endocrine and Metabolic Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS and Università Cattolica del Sacro Cuore, Rome, Italy
2 Azienda USL of Modena, Sassuolo Hospital, Sassuolo, Italy
3 Diabetes and Diabetic Foot Care Unit, ASUGI, Monfalcone, Italy
4 National Board Member of FAND (Italian Association for the Rights of Diabetic People), Roma, Italy
5 Department of Endocrinology and Metabolic Diseases, AO SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy
6 Order of Psychologists of Lazio, Rome, Italy
7 Italian Society of General Medicine (SIMG), Florence, Italy
8 Territorial Diabetology Unit, AUSL Ferrara, Ferrara, Italy
9 Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy
10 Diabetes Unit, Niguarda Cà Granda Hospital, Milan, Italy
11 Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy
12 Institute of Management, Scuola Superiore Sant’Anna, Pisa, Italy
13 Patient Advocacy Lab, ALTEMS – Università Cattolica del Sacro Cuore, Rome, Italy
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引用本文:简喜超, 简扬, 邓呈亮. 2025版《中国糖尿病足防治实践指南》解读[J]. 中华医学美学美容杂志, 2026, 32(2): 99-103. DOI: 10.3760/cma.j.cn114657-20251215-00266.
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This report outlines the proceedings of an industry-sponsored symposium (held at the European Wound Management Association 2023 Conference) during which an international panel of scientific and clinical experts shared research data relating to the mechanism of action of negative pressure wound therapy (NPWT) and its clinical relevance. The speakers also shared their clinical experiences of using a canister-based, singleuse NPWT system in the management of both open wounds and closed surgical incision sites.
Speakers: (Clockwise from top left) Marino Ciliberti (chair), Amit Gefen , Anette Svensson Henriksson and Sanna Kouhia
Marino Ciliberti is MD Surgeon, Director of the Wound Care Centre, Rete Aziendale Di Riparazione Tissutale, Aslnapoli3sud, Gragnano, Campania, Italy;
Amit Gefen is Professor of Biomedical Engineering Herbert J Berman Chair in Vascular Bioengineering, Department of Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel; Skin Integrity Research Group (SKINT), University Centre for Nursing and Midwifery, Department of Public Health and Primary Care, Ghent University, Ghent, Belgium; Department of Mathematics and Statistics, Faculty of Sciences, Hasselt University, Hasselt, Belgium;
Anette Svensson Henriksson is Senior Scientist, Research & Development, Mölnlycke Healthcare, Gothenburg, Sweden;
Sanna Kouhia is Consultant in Vascular Surgery, Consultant in General Surgery, Specialist in Wound Care, Espoo, Finland
Our companion article outlines how metformin use can lead to a clinically significant deficiency in vitamin B12, and describes the problems this can cause. In this comment, we outline a project conducted in four primary care practices that aimed to improve metformin-related vitamin B12 deficiency detection rates in people with diabetes.
Shafali Khanom
Medical Student, University of Sofia, Bulgaria
Mosammath Monira Khatun
Medical Student, Imperial College London
Reshma Rasheed
GP, Chapel Street Surgery, Billericay
Citation:
Khanom S, Khatun MM, Rasheed R (2023) Improving detection rates of vitamin B12 deficiency caused by metformin. Journal of Diabetes Nursing
[Early view publication]
Melanie Burcham
While it is rare for both a parent and their child to have type 1 diabetes, paediatric diabetes teams may come across this situation. This article explores the experiences and opinions of four such parents following their child’s diagnosis, and how diabetes teams can meet the needs of these families. The themes discussed include the emotional impact of a child’s type 1 diagnosis on the parent, and how their experience and knowledge of the condition can benefit their child, as well as providing challenges resulting from the parent’s own trauma of living with diabetes. Strategies for supporting and educating families following a child’s diagnosis, which include acknowledging the personal experiences that a parent with type 1 diabetes can bring and discussing emotional health routinely, are explored.
Citation: Burcham M (2023)
When your child is diagnosed with type 1 diabetes: Experiences of parents who also have the condition. Journal of Diabetes Nursing 27: JDN288
Article points
1. When a parent with type 1 diabetes has a child diagnosed with the same condition, the paediatric diabetes team must consider how to meet the particular needs of that family.
2. The parent’s experience of type 1 diabetes may bring feelings of guilt and grief, and other emotional challenges, as well as potential benefits arising from their knowledge of the condition. Paediatric diabetes teams need to acknowledge the additional pressures that such parents face, identify their specific needs and evaluate how to support the family.
Key words
- Children with type 1 diabetes
- Diabetes distress
- Emotional support
- Parents with type 1 diabetes
Authors
Melanie Burcham, Paediatric Diabetes Clinical Nurse Specialist, Royal Free Hospital, London.
Aim: The objective of this study is to evaluate the safety and efficacy of a negative pressure wound therapy (NPWT) device in trauma and other complex wounds.
Methods: The present clinical study is a prospective, interventional study conducted at a tertiary care center. NPWT was applied and the Bates-Jensen Score was calculated to assess the improvement in
wound healing outcomes.
Results: Twenty-two patients were assessed. The outcomes demonstrated that NPWT treatment reduced Bates-Jensen score when compared with the baseline score.
Conclusion: This indicates that NPWT therapy facilitates wound healing by increasing granulation tissue formation and lowering wound exudate levels.
Key words:
■Bates-Jensen Score,
■Negative pressure wound therapy
■Trauma Wounds
■Wound Exudate
■Wound Healing
■Wound management
Sushma Sagar is Professor, All India Institute of Medical Science, New Delhi, India;
Parvez Mohi Ud Din Dar is Senior Resident, All India Institute of Medical Sciences New Delhi;
Subodh Kumar is Professor, All India Institute of Medical Sciences New Delhi;
Amit Gupta is Professor, All India Institute of Medical Sciences New Delhi
This article first appeared in our sister publication Wounds Asia in volume 5 issue 2. Citation: Improved Bates-Jensen score following negative pressure wound therapy on wounds of various aetiologies: an experience from a tertiary care centre. Wounds Asia 5(3): 15–21
Nazli Parast, Pamela Walsh
This article presents a quality improvement study focused on developing a health literacy assessment tool for certified diabetes educators in Canada to use during virtual consultations with people diagnosed with type 2 diabetes. The study aims to improve healthcare professionals’ understanding of their patients’ health literacy levels in order to provide tailored education and support for diabetes self-management. It explores the prevalence and management of diabetes, the role of health literacy and education in diabetes management, and the significance of the study. The research questions address the effectiveness and practicality of existing health literacy tools in virtual consultations, the potential for improvement or development of a new tool, and the implications for patient-centred care in diabetes education. The article emphasises the importance of assessing health literacy in virtual consultations to ensure effective diabetes management and better outcomes for individuals living with the condition.
Citation: Parast N, Walsh P (2023) Empowering diabetes selfmanagement: A qualitative study on developing and evaluating health literacy tools for virtual consultations with certified diabetes educators. Journal of Diabetes Nursing 27: JDN311
1. A study was conducted to develop a tool to assess during virtual consultations the health literacy of people with type 2 diabetes.
2. For healthcare professionals to provide effective diabetes education, it is essential that an understanding of an individual’s health literacy is gained.
3. Through a quality improvement approach, participating certified diabetes educators helped to develop a new tool with the potential to help ensure effective self-management and improved outcomes.
- Certified diabetes educators
- Health literacy tools
- Type 2 diabetes
Nazli Parast, Advanced Practice
Nurse and Diabetes
Nurse Educator, and Pamela
Walsh, Associate Professor,
Athabasca University, Athabasca,
Alberta, Canada.
A pre-specified secondary analysis of the DELIVER randomised controlled trial in 5788 people with heart failure with mildly reduced or preserved ejection fraction, with or without type 2 diabetes, explored the implications of early eGFR changes after initiation of dapagliflozin on later cardiovascular and renal risk. As expected, from baseline to 1 month, eGFR declines of >10% were more common in those actively treated with dapagliflozin than in those treated with placebo, occurring in 40% versus 25%. In placebo recipients, experiencing an initial eGFR reduction of >10% was associated with a higher risk of major adverse cardiovascular events. However, in those treated with dapagliflozin, although an initial eGFR reduction of >10% was common, this was not associated with adverse cardiovascular or renal outcomes compared to those treated with dapagliflozin who experienced smaller initial reductions in eGFR. The authors concluded that these findings reinforce the advice, based on earlier studies in those at high risk of cardiorenal disease, that SGLT2 inhibitors need not usually be discontinued or interrupted in response to an initial eGFR reduction. Other studies and editorials have concluded that routine monitoring of renal function is not required after initiating SGLT2 inhibitors unless volume depletion is considered a risk.
Pam Brown
GP in Swansea
Citation: Brown P (2023) Diabetes
Distilled: DELIVERing reassurance that early eGFR reductions with SGLT2 inhibitors should not prompt drug discontinuation. Diabetes & Primary Care 25: 205–7
伤口世界平台生态圈,以“关爱人间所有伤口患者”为愿景,连接、整合和拓展线上和线下的管理慢性伤口的资源,倡导远程、就近和居家管理慢性伤口,解决伤口专家的碎片化时间的价值创造、诊疗经验的裂变复制、和患者的就近、居家和低成本管理慢性伤口的问题。
2019广东省医疗行业协会伤口管理分会年会
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