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28 8月 2019

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Author : 伤口世界

擅长疾病：糖尿病足；慢性、难愈合性伤口治疗。执业经历：

国际伤口治疗师。从事慢性伤口工作10年余，曾赴新加坡中央医院足病中心进修。擅长治疗糖尿病足及相关的慢性、难愈合性创面的治疗，具有丰富的临床经验。

Latest from 伤口世界

Development of chilblain lesions during the COVID-19 pandemic is strongly associated with cold weather: a retrospective analysis of patients from a single centre in the USA
An illustrative case of pseudo-chilblains in tropical Singapore: what is its significance?
Frostbite secondary to antimycobacterial-induced peripheral neuropathy: a case report
Cyclic cryotherapy with vitamin D facilitates early rehabilitation after total knee arthroplasty
Construction and validation of a risk prediction model for soldiers with frostbite in northeast China: a cross-sectional study

K2 Content

Development of chilblain lesions during the COVID-19 pandemic is strongly associated with cold weather: a retrospective analysis of patients from a single centre in the USA 2025-01-23 00:00
An illustrative case of pseudo-chilblains in tropical Singapore: what is its significance? 2025-01-22 00:00

This article is excerpted from the Singapore Medical Journal ¦ Volume 65 ¦ Supplement 1 ¦ March 2024 by Wound World.
Frostbite secondary to antimycobacterial-induced peripheral neuropathy: a case report 2025-01-20 00:00

Shahad N Alanazi1 , Dana A Bali1 , Nawaf M Alwagdani2 , Youssof Mal3 , Maram T Alkhatieb4 , Hattan A AlJaaly1 , Zahir T Fadel1

1 Division of Plastic Surgery, Department of Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia; 2Department of Orthopedic Surgery, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia; 3Department of Clinical Biochemistry, Faculty of Medicine in Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia; 4Department of Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia Received October 24, 2023; Accepted March 13, 2024; Epub April 15, 2024; Published April 30, 2024

Abstract: This case report describes a unique scenario in which antimycobacterial-induced peripheral neuropathy (PN) culminates in severe bilateral foot frostbite. Drug-induced peripheral neuropathy (DIPN) is explored in the context of TB treatment, highlighting the role of medications such as isoniazid (INH) and their potential to cause PN. The report highlights the importance of identifying PN in patients undergoing antimycobacterial treatment. Early recognition and proper management of PN is crucial to prevent complications. Notably, the report advocates for patient education regarding medication side effects and avoiding harmful practices, such as ice immersion, to alliviate neuropathic pain. Emphasis is directed towards the need for a multidisciplinary approach to patient care and a focus on preventative strategies to improve patient outcomes and avoid severe debilitating complications.

Keywords: Frostbite, peripheral neuropathy, isoniazid (INH), drug-induced peripheral neuropathy (DIPN)

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主任医师、教授、博导，南方医科大学第三附属医院（广东省骨科医院）院长

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主任医师、教授、博导，南方医科大学第三附属医院（广东省骨科医院）院长

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