Mateo Ve´ lez-Fort,1,3 Lee Cossell,1,3 Laura Porta,1 Claudia Clopath,1,2 and Troy W. Margrie1,4,*
1 Sainsbury Wellcome Centre, University College London, London, UK
2 Bioengineering Department, Imperial College London, London, UK
3 These authors contributed equally
4 Lead contact
*Correspondence: 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。
https://doi.org/10.1016/j.cell.2025.01.032
SUMMARY
Knowing whether we are moving or something in the world is moving around us is possibly the most critical sensory discrimination we need to perform. How the brain and, in particular, the visual system solves this motion-source separation problem is not known. Here, we find that motor, vestibular, and visual motion signals are used by the mouse primary visual cortex (VISp) to differentially represent the same visual flow information according to whether the head is stationary or experiencing passive versus active translation. During locomotion, we find that running suppresses running-congruent translation input and that translation signals dominate VISp activity when running and translation speed become incongruent. This cross-modal interaction between the motor and vestibular systems was found throughout the cortex, indicating that running and translation signals provide a brain-wide egocentric reference frame for computing the internally generated and actual speed of self when moving through and sensing the external world.
擅长疾病：在烧伤、创伤后瘢痕整形、先天性畸形、面部及躯干美容等方面临床经验丰富，具有较强的解决本专业疑难病例的能力及显微外科手术能力。
擅长领域：（1）耳廓、乳房、阴茎、鼻部等体表器官再造（2）体表软组织肿瘤切除与美容修复（3）脂肪移植与面部年轻化（4）血管瘤、鲜红斑痣等激光美容
对烧伤外科、整形外科及美容外科有较深的造谐，擅长大面积严重烧伤的救治，唇腭裂修复、软组织缺损的修复及各类美容整形和再造整形手术，每年完成大小各类手术360余例。
从事整形外科近30年，留美多年，熟练掌握面部美容、除皱、乳房整形、脂肪抽吸等各类美容整形外科手术及各种非手术美容(如肉毒毒素A注射除皱等)，对外生殖器整形与再造，两性畸形和易性症的手术治疗等有较深入研究。
伤口世界平台生态圈，以“关爱人间所有伤口患者”为愿景，连接、整合和拓展线上和线下的管理慢性伤口的资源，倡导远程、就近和居家管理慢性伤口，解决伤口专家的碎片化时间的价值创造、诊疗经验的裂变复制、和患者的就近、居家和低成本管理慢性伤口的问题。
2019广东省医疗行业协会伤口管理分会年会
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