蒋宙男1 戚吉妮!徐伟力’周玥3 张菊芳!浙江中医药大学第四临床医学院,杭州 310053;2杭州市第一人民医院城北院区整形外科,杭州 311203:解放军联保障部队第九〇三医院整形外科,杭州 310013:浙江大学医学院附属杭州市第一人民医院整形外科，杭州 310006通信作者:张菊芳，Email:该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。:10.3760/cma.j.issn.1671-0290.2023.02.021

刘鹏林1 陈天丽2 张立泽1 尤雯丽1 赵刚1

1青岛大学附属医院肛肠科,青岛 266555;2青岛市黄岛区中心医院皮肤科,青岛 266555

通信作者:刘 鹏 林,Email:该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。;赵 刚,Email:该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

DOI:10.3760

/cma.j.issn.1671-0290.2023.02.022

李宇 万若愚 陈宇凌 董薪 李利

四川大学华西医院皮肤性病科,成都 610041

通信作者:李利,Email:该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

基金项目:四川大学华西医院学科卓越发展135工程项目基金资助项目(ZY2016106)

DOI:10.3760/cma.j.issn.1671-0290.2023.05.018

李明玉  张波

【摘要】 瘢痕癌（马乔林溃疡）多由瘢痕溃疡恶变而成，临床表现以溃疡经久不愈为主。瘢痕癌的致病因素和发病机制尚未明确，目前的诊疗方案亦尚未达成共识。该文报道 1 例 51 岁女性瘢痕癌患者，其于 25 年前曾有大面积的皮肤烧伤史，于入院前 3 个月发现右侧小腿后上方肿物，局部破溃，难以愈合，经活组织病理学检查确诊为瘢痕癌。患者接受局部调强放射治疗（瘢痕癌病灶 + 转移淋巴结 66 Gy/33F，亚临床病灶 50 Gy/25F），治疗结束后复查 MRI 示肿物较前缩小，随访情况稳定。

【关键词】 瘢痕癌；调强放射治疗；个案报道

Intensity-modulated radiation therapy for scar carcinoma: a case report Li Mingyu， Zhang Bo. Department of Radiotherapy，

The First Hospital of Xingtai， Xingtai 054000， China

【Abstract】

Scar carcinoma （Marjolin ulcer） is mostly derived from the malignant transformation of scar ulcer with its nonhealing as the main clinical manifestation. The factors and mechanisms of scar carcinoma remain elusive. Currently， no consensus has been reached on the diagnosis and treatment of scar carcinoma. In this article， the diagnosis and treatment of a 51-year-old female patient with scar carcinoma were reported. She had a history of extensive skin burns 25 years ago. A mass was found in the posterior upper part of the right calf 3 months before admission， with local rupture and difficulty of wound healing. She was diagnosed with scar carcinoma by biopsy. The patient received local intensity-modulated radiation therapy （IMRT） at 66 Gy/33F for scar carcinoma + metastatic lymph nodes and 50 Gy/25F for subclinical lesions. After local IMRT， MRI showed that the mass was smaller and the patient remained physically stable during subsequent follow-up.

【Key words】 Scar carcinoma； Intensity-modulated radiation therapy； Case report