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主任医师、教授、博导，南方医科大学第三附属医院（广东省骨科医院）院长

中德骨科伤口管理学校校长

广东省骨科研究院运动医学研究所所长

广东省内运动医学专业唯一的博士研究生导师

美国哈弗大学医学院骨科访问学者

专业特长处于省内领先、国内或国际先进水平以上

2018年获得“国之名医卓越建树”荣誉称号

2017年被评为全国卫生计生系统先进工作者、广东省医学领军人才

中国医师协会运动医师分会副会长

STCOT中国部运动医学分会副主任委员

广东省医学会关节外科分会主任委员

广东省医学会运动医学会分会名誉主任委员

独立承担过国家“863”课题，主持过10余项省、部级科研项目

多份专业杂志编委
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近红外二区荧光导航手术在足踝外科中的应用初探 2026-03-31 00:00

樊潇霄a,b,# , 杨杰c,# , 倪沪桅b,# , 夏启铭a , 刘孝龙a , 吴天翔b , 李霖c , Paras N. Prasad d , 刘超c, * , 林辉a,e,f, * , 钱骏a,b, *

a Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China

b Centre for Optical and Electromagnetic Research & International Research Center for Advanced Photonics, College of Optical Science and Engineering, Zhejiang University, Hangzhou 310058, China

c Department of Orthopedics, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China

d Institute for Lasers, Photonics, and Biophotonics, Department of Chemistry, State University of New York, Buffalo, NY 14260-3000, USA

e Zhejiang Engineering Research Center of Cognitive Healthcare, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China

f College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, China

摘要近红外二区（NIR-II; 900~1880 nm）窗口的光学成像，是目前生物医学成像领域的热门研究课题。本研究旨在探索 NIR-II荧光成像在足踝外科手术中的应用价值。我们开发了一套实验室自建的NIR-II荧光手术导航系统，并将其用于足踝外科手术导航。相比于近红外一区（NIR-I）荧光图像，该系统获得的NIR-II 荧光图像，拥有更高空间频率的信息以及更高的信号背景比（SBR）。本文的研究结果表明，NIR-II成像可为外科医生提供对比度更高、探测深度更大的图像。本研究纳入了三种临床应用场景（糖尿病足、跟骨骨折以及下肢创伤）。利用NIR-II荧光成像技术，我们在糖尿病足出现形态学改变前就观察到了缺血区域，精准定位了手术切口中缺血区域的边界，并全面评估了皮瓣的血供情况。NIR-II荧光成像能够帮助外科医生精确判断手术切缘，提早发现缺血性病变，并动态追踪灌注过程。我们认为，便携且可靠的 NIR-II荧光成像设备以及更多功能性荧光探针，可在精准手术中发挥关键作用。 © 2024 THE AUTHORS. Published by Elsevier LTD on behalf of Chinese Academy of Engineering and Higher Education Press Limited Company. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

关键词近红外二区荧光成像足踝外科手术吲哚菁绿影像引导手术

A R T I C L E I N F O

Article history: Received 19 January 2024 Revised 11 April 2024 Accepted 14 April 2024 Available online 26 April 2024

分子显像在糖尿病及其并发症中的应用研究进展 2026-03-30 00:00

李军1 刘兴党2

1北京大学深圳医院核医学科，深圳 518036；2 复旦大学附属华山医院核医学科，上海市核医学质量控制中心，上海 200040

通信作者：刘兴党，Email：该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

【摘要】糖尿病是一种慢性代谢性疾病，全球有超过 4 亿的糖尿病患者。1 型糖尿病和 2 型糖尿病的发病机制与胰岛 β 细胞的减少和功能受损相关。糖尿病患者若长时间高血糖，则会导致心血管疾病、神经病变、糖尿病足及其他并发症。笔者就不同种类的 PET 或 SPECT 分子显像在糖尿病患者的胰岛 β 细胞的功能监测以及冠状动脉病变、心肌病、自主神经病变、大脑异常和糖尿病足的早期精准诊断中的应用研究进展进行综述。

【关键词】糖尿病；糖尿病并发症；分子显像；正电子发射断层显像术；体层摄影术，发射型计算机，单光子

DOI：10.3760/cma.j.cn121381−202007026−00159

Li Jun1 , Liu Xingdang2

1 Department of Nuclear Medicine, Peking University Shenzhen Hospital, Shenzhen 518036, China;

2 Department of Nuclear Medicine, Huashan Hospital, Fudan University, Shanghai Nuclear Medicine Quality Control Center, Shanghai 200040, China

Corresponding author: Liu Xingdang, Email: 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

【Abstract】 Diabetes mellitus is a chronic and metabolic disease affecting more than 400 million people in the world. The pathogenesis of type 1 and type 2 diabetes mellitus is associated with the decrease or functional impairment of pancreatic β cells. With long-term hyperglycemia, diabetic patients will develop cardiovascular disease, neuropathy, diabetic foot and other complications. This paper reviews the application research progress of different types of PET and SPECT molecular imaging in the function monitoring of pancreatic β cells, and early diagnosis of diabetic complications such as coronary artery disease, cardiomyopathy, autonomic neuropathy, brain abnormalities and diabetic foot in diabetic patients.

【Key words】 Diabetes mellitus; Diabetes complications; Molecular imaging; Positron emission tomography; Tomography, emission-computed, single-photon

DOI：10.3760/cma.j.cn121381−202007026−00159
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保持引流管通畅，进行有效引流

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18 10月 2019

Author : 伤口世界

1、保持引流管通畅，负压引流管保持负压状态，维持有效的引流。

2、防止引流管受压、扭曲、堵塞，动态观察。挤捏法：护士站在于患者引流侧，双手握住距留置管路端口处10－15cm的引流管，挤压时由上至下，两手交替，一只手用力捏住引流管，使引流管暂时处于闭塞状态，另一只手匀速快速挤压引流管。

3、当引流管堵塞时可用手挤压胶管或用注射器冲洗，若引流管漏气，及时处理，预防并发症发生。

因积液较稠或坏死，组织、血凝块堵塞引流管时，可用注射器抽适量生理盐水冲洗，保持通畅。

有效固定引流管，进行宣教

1、妥善固定引流管，防止其脱落。固定方法：用高举平台法将引流管固定于皮肤上。为防止皮肤破损，或对各类胶布过敏者，可在固定处，外敷透明皮肤膜，保护皮肤，再将引流管固定于透明膜上，更有利于管路的稳固。

2、将接于引流管上的各种引流装置挂于易看见、不影响病人翻身的位置。

3、向患者及家属宣教，放置引流管的目的、重要性，强化医疗安全意识，防止高龄患者及麻醉未清醒患者将引流管拔除。并交待患者注意事项翻身或活动时一定要先保持引流管的有效活动距离再进行翻身和其他活动。

作者：胡琴

编辑：胡海涛

图文来源：作者和编辑提供

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近红外二区荧光导航手术在足踝外科中的应用初探 2026-03-31 00:00

樊潇霄a,b,# , 杨杰c,# , 倪沪桅b,# , 夏启铭a , 刘孝龙a , 吴天翔b , 李霖c , Paras N. Prasad d , 刘超c, * , 林辉a,e,f, * , 钱骏a,b, *

a Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China

b Centre for Optical and Electromagnetic Research & International Research Center for Advanced Photonics, College of Optical Science and Engineering, Zhejiang University, Hangzhou 310058, China

c Department of Orthopedics, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China

d Institute for Lasers, Photonics, and Biophotonics, Department of Chemistry, State University of New York, Buffalo, NY 14260-3000, USA

e Zhejiang Engineering Research Center of Cognitive Healthcare, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China

f College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, China

摘要近红外二区（NIR-II; 900~1880 nm）窗口的光学成像，是目前生物医学成像领域的热门研究课题。本研究旨在探索 NIR-II荧光成像在足踝外科手术中的应用价值。我们开发了一套实验室自建的NIR-II荧光手术导航系统，并将其用于足踝外科手术导航。相比于近红外一区（NIR-I）荧光图像，该系统获得的NIR-II 荧光图像，拥有更高空间频率的信息以及更高的信号背景比（SBR）。本文的研究结果表明，NIR-II成像可为外科医生提供对比度更高、探测深度更大的图像。本研究纳入了三种临床应用场景（糖尿病足、跟骨骨折以及下肢创伤）。利用NIR-II荧光成像技术，我们在糖尿病足出现形态学改变前就观察到了缺血区域，精准定位了手术切口中缺血区域的边界，并全面评估了皮瓣的血供情况。NIR-II荧光成像能够帮助外科医生精确判断手术切缘，提早发现缺血性病变，并动态追踪灌注过程。我们认为，便携且可靠的 NIR-II荧光成像设备以及更多功能性荧光探针，可在精准手术中发挥关键作用。 © 2024 THE AUTHORS. Published by Elsevier LTD on behalf of Chinese Academy of Engineering and Higher Education Press Limited Company. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

关键词近红外二区荧光成像足踝外科手术吲哚菁绿影像引导手术

A R T I C L E I N F O

Article history: Received 19 January 2024 Revised 11 April 2024 Accepted 14 April 2024 Available online 26 April 2024
分子显像在糖尿病及其并发症中的应用研究进展 2026-03-30 00:00

李军1 刘兴党2

1北京大学深圳医院核医学科，深圳 518036；2 复旦大学附属华山医院核医学科，上海市核医学质量控制中心，上海 200040

通信作者：刘兴党，Email：该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

【摘要】糖尿病是一种慢性代谢性疾病，全球有超过 4 亿的糖尿病患者。1 型糖尿病和 2 型糖尿病的发病机制与胰岛 β 细胞的减少和功能受损相关。糖尿病患者若长时间高血糖，则会导致心血管疾病、神经病变、糖尿病足及其他并发症。笔者就不同种类的 PET 或 SPECT 分子显像在糖尿病患者的胰岛 β 细胞的功能监测以及冠状动脉病变、心肌病、自主神经病变、大脑异常和糖尿病足的早期精准诊断中的应用研究进展进行综述。

【关键词】糖尿病；糖尿病并发症；分子显像；正电子发射断层显像术；体层摄影术，发射型计算机，单光子

DOI：10.3760/cma.j.cn121381−202007026−00159

Li Jun1 , Liu Xingdang2

1 Department of Nuclear Medicine, Peking University Shenzhen Hospital, Shenzhen 518036, China;

2 Department of Nuclear Medicine, Huashan Hospital, Fudan University, Shanghai Nuclear Medicine Quality Control Center, Shanghai 200040, China

Corresponding author: Liu Xingdang, Email: 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

【Abstract】 Diabetes mellitus is a chronic and metabolic disease affecting more than 400 million people in the world. The pathogenesis of type 1 and type 2 diabetes mellitus is associated with the decrease or functional impairment of pancreatic β cells. With long-term hyperglycemia, diabetic patients will develop cardiovascular disease, neuropathy, diabetic foot and other complications. This paper reviews the application research progress of different types of PET and SPECT molecular imaging in the function monitoring of pancreatic β cells, and early diagnosis of diabetic complications such as coronary artery disease, cardiomyopathy, autonomic neuropathy, brain abnormalities and diabetic foot in diabetic patients.

【Key words】 Diabetes mellitus; Diabetes complications; Molecular imaging; Positron emission tomography; Tomography, emission-computed, single-photon

DOI：10.3760/cma.j.cn121381−202007026−00159
Prediabetes prevalence and awareness by race, ethnicity, and educational attainment among U.S. adults 2026-03-23 00:00

Taynara Formagini1,2 *, Joanna Veazey Brooks2,3,4 , Andrew Roberts2,5 , Kai McKeever Bullard6 , Yan Zhang6 , Ryan Saelee6 and Matthew James O'Brien7

1 Department of Family Medicine, University of California San Diego, San Diego, CA, United States,

2 Department of Population Health, University of Kansas School of Medicine, Kansas City, KS, United States, 3University of Kansas Cancer Center, Kansas City, KS, United States, 4Division of Palliative Medicine, University of Kansas School of Medicine, Kansas City, KS, United States, 5Aetion Inc., New York, NY, United States, 6Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, CDC, Atlanta, GA, United States, 7 Department of Medicine, Division of General Internal Medicine and Geriatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, United States

Introduction: Racial and ethnic minority groups and individuals with limited educational attainment experience a disproportionate burden of diabetes. Prediabetes represents a high-risk state for developing type 2 diabetes, but most adults with prediabetes are unaware of having the condition. Uncovering whether racial, ethnic, or educational disparities also occur in the prediabetes stage could help inform strategies to support health equity in preventing type 2 diabetes and its complications. We examined the prevalence of prediabetes and prediabetes awareness, with corresponding prevalence ratios according to race, ethnicity, and educational attainment.

Methods: This study was a pooled cross-sectional analysis of the National Health and Nutrition Examination Survey data from 2011 to March 2020. The final sample comprised 10,262 U.S. adults who self-reported being Asian, Black, Hispanic, or White. Prediabetes was defined using hemoglobin A1c and fasting plasma glucose values. Those with prediabetes were classified as “aware” or “unaware” based on survey responses. We calculated prevalence ratios (PR) to assess the relationship between race, ethnicity, and educational attainment with prediabetes and prediabetes awareness, controlling for sociodemographic, health and healthcare-related, and clinical characteristics.

Results: In fully adjusted logistic regression models, Asian, Black, and Hispanic adults had a statistically significant higher risk of prediabetes than White adults (PR:1.26 [1.18,1.35], PR:1.17 [1.08,1.25], and PR:1.10 [1.02,1.19], respectively). Adults completing less than high school and high school had a significantly higher risk of prediabetes compared to those with a college degree (PR:1.14 [1.02,1.26] and PR:1.12 [1.01,1.23], respectively). We also found that Black and Hispanic adults had higher rates of prediabetes awareness in the fully adjusted model than White adults (PR:1.27 [1.07,1.50] and PR:1.33 [1.02,1.72], respectively). The rates of prediabetes awareness were consistently lower among those with less than a high school education relative to individuals who completed college (fully-adjusted model PR:0.66 [0.47,0.92]).

Discussion: Disparities in prediabetes among racial and ethnic minority groups and adults with low educational attainment suggest challenges and opportunities for promoting health equity in high-risk groups and expanding awareness of prediabetes in the United States.

KEYWORDS

prediabetes, prediabetes awareness, diabetes-related disparities, race and ethnicity, educational attainment

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2019广东省医疗行业协会伤口管理分会年会

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2019年6月15日中国广州
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Custom Mod Mega1

主任医师、教授、博导，南方医科大学第三附属医院（广东省骨科医院）院长