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Profiling of Petroselinum sativum (mill.) fuss phytoconstituents and assessment of their biocompatibility, antioxidant, anti-aging, wound healing, and antibacterial activities

This article is excerpted from the《Frontiers in Nutrition》 by Wound World

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This article is excerpted from the《Frontiers in Neurology》 by Wound World

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This article is excerpted from the《Frontiers in Neurology》 by Wound World

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This article is excerpted from the《Frontiers in Neurology》 by Wound World

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Robotic-assisted laparoscopic repair of a congenital rectourethral fistula with duplicated urethra 2026-09-11 00:00

Rohan G. Bhalla ^a , Belinda Li ^{b,d, *}, Mark C. Adams^b , Wallace W. Neblett^c , John C. Thomas ^b

Summary

Objective

To describe our experience with robot-assisted laparoscopic transperitoneal repair of a congenital rectourethral fistula in a pediatric patient with a urethral duplication.

Methods

The patient is a 2-year-old male with a past medical history of Tetralogy of Fallot presenting with a febrile urinary tract infection (UTI). He was diagnosed with urethral duplication and a rectourethral fistula by voiding cystourethrogram (VCUG). The parents were counseled on various options and agreed to proceed with a robotic repair.

Results

Robotic-assisted transperitoneal rectourethral fistula repair was performed. The procedure time was 229 min with an estimated blood loss (EBL) of 15 mL. His postoperative course was unremarkable. At his 2- week follow-up, the urethral catheter was removed and the patient was voiding normally and having normal bowel movements.

Conclusion

Congenital rectourethral fistula with urethral duplication is a rare anomaly with only a few reports in the literature. Pediatric robotic-assisted trans-peritoneal rectourethral fistula repair is a technically feasible approach in infants with minimal morbidity that allows for excellent visualization and avoids open repair.
Complete diphallia: How to proceed? 2026-09-10 00:00

Antonio Macedo Jr ^a,b , Se´rgio Leite Ottoni ^b , Paula Cartaxo Barros Camilato ^b , Hugo Santiago Crespo Ganchozo ^b , Gilmar Garrone^b , Ricardo de Mattos Marcondes ^b , Marcela Leal da Cruz ^{b, *}

Summary

Introduction

Diphallia is a rare anomaly. It has a range of appearances from a small accessory penile to complete duplication.

Methods

We present a 2 year-old boy with complete penile duplication. The left penile was the largest. NMR (Nuclear Magnetic Resonance) suggested one corporal body for each penile and VCUG (Voiding Cystourethrogram) showed a normal urethra in the right penile and stricture at glandular and mid penile urethra of the left penis. A Y confluence to bulbar urethra was observed confirming only one prostate and bladder.

Results

The cystoscopy through the right penile identified the urethral confluence in the bulbar area. We performed a meatotomy in the left penile to insert the cystoscope and confirmed the blind ending urethra. We decided to remove this penile. The penile was degloved entirely and clamped and took out the corpora at the base.

Discussion

Diphallia can have three presentations: only glans duplication, bifid diphallia and complete diphallia (two corpora cavernosa and a corpus spongiosum for each penile). In our case, each penile presented only one corpora cavernosa and the decision taken was based on urethral patency.

Conclusion

The treatment should always be planned individually whereas associated anomalies with the goal of attaining satisfactory functional and cosmetic.
Can portable ultrasound bladder scanner be applied to young children less than three years old? 2026-09-09 00:00

Minh-Tung Do ^a , Louis Kim ^b , Young Jae Im ^a,b , Kwanjin Park^{a,b, *}

Summary

Introduction The bladder scanner (BS), a portable ultrasound device specialized in bladder volume measurement, has been developed and applied to clinical assessment of postvoid residual urine, which is a requisite in evaluating patients with voiding dysfunction.

However, experiences in the application of the BS to the pediatric population remain limited despite commonly encountered reluctance to catheterization. This prospective observational study aimed to evaluate the correlation and accuracy of the newly developed pediatric module of the BS (BioCon-900) in measuring bladder volume in children 0e6 years.

Materials and methods

This study included 29 patients scheduled to undergo preventive untethering for their spinal dysraphism. When they undergo cystometry for the confirmation of normal neurologic function, bladder volume was measured by BS when recorded volume infusion reached each quartile of the age-adjusted estimated bladder capacity (EBC). The difference (bias) between measured and infused volume was expressed as a percentage of EBC (%EBC). The correlation coefficient and the Bland_Altman plot were obtained to determine the discriminating power and accuracy, respectively. The acceptable limit was set as 30%EBC.

Results

A strong correlation between the measured and infused volume (r = 0.95, P < 0.001) was found for the entire age range. This excellent correlation remained comparable between children less than three years and the older ones. Bladder volume tended to be overestimated, and the mean bias was 33 ± 22.3%EBC, and it became higher with increasing quartiles. The accuracy was acceptable in all ranges of measurement in the older group and first and second quartiles in the younger one.

Discussion

We have first evaluated the potential use of BS in 0_3 years old children and compared the results with 4_6- year-old children in whom the accuracy of BS has been demonstrated. The strong point of our study was the inclusion of data spanning all quartiles of bladder volume. The use of infused volume as reference enabled us to assess the accuracy in a more precise way than the use of ultrasound. Despite the good discriminating power, the accuracy was not acceptable in higher quartiles in the younger group. If the trend of overestimation especially higher volume, could be understood prior to measurement, it would be helpful to assume the real val.

Conclusions

The children’s module in BS showed excellent discriminating power and generally acceptable accuracy in more than four-year-old children. This may lose accuracy in higher quartiles among less than three years old children.

Custom Mod Mega1

主任医师、教授、博导，南方医科大学第三附属医院（广东省骨科医院）院长

文献精选

Profiling of Petroselinum sativum (mill.) fuss phytoconstituents and assessment of their biocompatibility, antioxidant, anti-aging, wound healing, and antibacterial activities

Early nociceptive evoked potentials in symptomatic and asymptomatic transthyretin mutation carriers

Small and large fiber neuropathy in adults with myotonic dystrophy type 1

Which Method for Diagnosing Small Fiber Neuropathy?

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Custom Mod Mega1

主任医师、教授、博导，南方医科大学第三附属医院（广东省骨科医院）院长

文献精选

Profiling of Petroselinum sativum (mill.) fuss phytoconstituents and assessment of their biocompatibility, antioxidant, anti-aging, wound healing, and antibacterial activities

Early nociceptive evoked potentials in symptomatic and asymptomatic transthyretin mutation carriers

Small and large fiber neuropathy in adults with myotonic dystrophy type 1

Which Method for Diagnosing Small Fiber Neuropathy?

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