大湾区慢性创面医护康标准化体系建设联盟,《中国科技论文》体表外科卷编辑委员会,黄广涛1,吴 军1,郇京宁1,2
(1.深圳大学第一附属医院(深圳市第二人民医院)烧伤整形科,广东深圳518000;2.上海交通大学医学院附属瑞金医院烧伤整形与创面修复科,上海200011)
摘要:负压封闭引流技术(negative pressure wound therapy, NPWT)自2017年国内首部烧伤外科应用专家共识发布以来,其技术类型与临床应用范围均取得了显著拓展。特别是在促进各类急慢性创面愈合及预防外科手术部位感染方面,已累积了大量高质量循证证据。为整合国内外最新研究成果与临床实践经验,规范操作标准,提升治疗水平,国内创面修复相关多学科领域的专家共同撰写了本更新版共识。本共识汇聚了国内多位在创面相关的多学科领域的专家,结合国内外最新研究成果,遵循严谨的循证医学原则,采用系统综述方法,聚焦于NPWT的技术分类、适应症、参数优化及并发症处理等核心议题。工作小组系统检索了PubMed、Web of Science、IEEE Xplore及中国知网等数据库中2015—2025年相关文献,共获得791篇。经去重、筛选,并根据纳入标准(临床研究、随机对照试验、meta分析及相关共识等)最终纳入210篇文献进行证据综合与评价。本共识旨在为创面修复相关学科的临床医生提供基于最新证据、统一且可操作的治疗方案与技术规范。共识内容充分结合了我国临床实践的现状与需求,以期推动NPWT在国内的合理、规范及高效应用,最终惠及广大患者。
关键词:负压封闭引流技术;手术部位感染;创面修复;手术切口并发症
利宝平,童 梅,林敏华
广州市海珠区妇幼保健院 广东广州
【摘要】腋臭微创清除术是当前治疗腋臭的常见方法,而专业到位的腋臭微创清除术护理,是提升手术效果、
加快患者康复进度的必要条件。本文主要对腋臭微创清除术的护理研究进展进行全面分析,重点阐明术前、术中、
术后等护理环节要点,以期为腋臭微创清除术护理实践提供相应指导依据。
【关键词】腋臭微创清除术;护理;研究进展
【收稿日期】2025 年 11 月 13 日 【出刊日期】2025 年 12 月 10 日 【DOI】10.12208/j.ijnr.20250621
A review of nursing research progress in minimally invasive surgery for axillary osmidrosis
Baoping Li, Mei Tong, Minhua Lin
Haizhu District Maternal and Child Health Care Hospital of Guangzhou, Guangzhou, Guangdong
【Abstract】Minimally invasive surgery for axillary osmidrosis is a common treatment for bromhidrosis. High-quality nursing care plays a crucial role in improving surgical outcomes and promoting patient recovery. This paper provides a comprehensive analysis of research progress in nursing care for minimally invasive axillary osmidrosis surgery, with a focus on preoperative, intraoperative, and postoperative nursing. The aim is to offer practical guidance for clinical nursing practice in this field.
【Keywords】Minimally invasive surgery for axillary osmidrosis; Nursing; Research progress
Alfredo E. Hoyos,MDD;Mauricio E. Perez Pachon,MDD; Matt Stefanelli,MD;Mariana Borras Osorio, MD; Justo Calderon Mendoza,MSc;Maria Paula Castiblanco,MD;Mateo Leon Machicado,MD;and Andres Pinzon Valero,MD
AbstractBackground: Despite the general safety of liposuction and fat grafting procedures,surgical-site infections (SSIs) remain a significant concern. These infections, ranging from minor to severe,can arise from various sources and pose a substantial burden. The overuse of antibiotics has led to increased antimicrobial resistance,highlighting the need for alternative infection prevention strategies like stabilized hypochlorous acid (s-HOCl). Objectives: The aim of the authors of this study is to evaluate the efficacy and safety of s-HOCl in preventing SSIs following liposculpture and other body contouring procedures. Methods: A prospective cohort study and matched control cohort were conducted at a single plastic surgery center in Bogota,Colombia (Dhara Clinic). Adult patients scheduled for liposculpture and fat grafting from January 2020 to December 2023 formed the intervention group,receiving s-HOCl as a washing solution for adipose grafts. A matched control cohort was drawn from patients who underwent similar procedures from January 2017 to December 2019 without s-HOCl. Data on demographics,surgical characteristics,and SSI outcomes were collected and analyzed. Results: A total of 1008 patients were included,with 502 in the s-HOCl group and 506 in the control group. The infection rate in the s-HOCl group was 0.2 per 100 grafted muscles, compared with 0.54 in the control group. Relative risk of SSIs in the s-HOCl group was 0.4,indicating a reduction in infection rates. The small absolute risk reduction of 0.59% underscores the clinical importance,considering SSIs, although rare,are severe and life-threatening events,with significant impact on outcomes and healthcare costs. A reduction in the severity of infection and the level of required treatment was also observed. Conclusions: s-HOCl demonstrated potential to reduce SSI risk following liposuction and fat grafting. This intervention offers a valuable alternative to antibiotics,effectively reducing infection rates and contributing to improved patient outcomes and public health in postantibiotic era.
王昳娜1,何振华1,周瑾1,孙晓芬2
1.绍兴文理学院元培学院,浙江 312000;2.浙江中医药大学附属第二医院
Research progress on the application of hypochlorous acid in wound care
WANG Yi'na,HE Zhenhua,ZHOU Jin,SUN Xiaofen
Shaoxing University,Yuanpei College,Zhejiang 312000 China
Keywords hypochlorous acid solution;wound;infection;bacterial biofilm;clinical application;review
摘要 介绍了次氯酸溶液的发展史、杀菌机制、特点、与其他伤口清洁消毒剂的比较、使用方法以及当前研究的不足,旨在为次氯酸
溶液在伤口治疗、护理中的应用提供依据。
关键词 次氯酸溶液;伤口;感染;细菌生物膜;临床应用;综述
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杨金燕1,孙丹1,夏婷婷1,施施1,杨育卉2,闫中强1.3
1.解放军总医院海南医院疾病预防控制科2.血液科,海南 三亚 572014;3.解放军总医院第二医学中心疾病预防控制科,北京 100039
摘要:次氟酸消毒剂以其强大的消毒杀菌能力和环境友好特性,在医疗领域得到广泛关注及应用。有效浓度的次氟酸不仅能高效杀灭细菌、病毒等微生物,同时具有低毒、无残留、低腐蚀性等优势,适用于各种精密设备及复杂的医疗场景。次氯酸消毒剂可用于儿科病房、血液透析室等重点医疗场所的环境消毒。此外,在口腔护理、伤口处理、手术部位消毒等领域展现了独特的优势。本文探讨了次氯酸消毒剂的性能,为其在医疗机构的合理应用提供参考。随着清洁消毒技术的不断进步和应用的深入拓展,次氟酸消毒剂在医疗领域的应用前景将更加广阔。
关键词:次氯酸;次氯酸消毒剂;医疗机构;理化性质;临床消毒
中图分类号:R187 文献标识码:A 文章编号:1005-4529(2025)03-0476-05
Progress of research on clinical application of hypochlorous acid disinfectant
YANG Jinyan*,SUN Dan,XIA Tingting,SHI Shi,YANG Yuhui,YAN Zhongqiang* Hainan Hos pital of PLAGeneral Hospital,Sanya ,Hainan 572014,China
Abstract: Hypochlorous acid disinfectant has been widely noticed and applied in the medical field due to its power-ful disinfecting and sterilizing ability and environmental friendly characteristics.Effective concentration of hypo-chlorous acid disinfectant can not only efficiently kill bacteria,viruses and other microorganisms, but also has theadvantages of low toxicity,no residue and low corrosion,which is suitable for all kinds of complicated equipmentand complex medical scenarios,It can be used for environmental disinfection in major medical places such as pedi-atric wards and hemodialysis rooms,In addition,it demonstrates unique advantages in the oral care,wound treat-ment, and surgical site disinfection, This article explores the properties of hypochlorous acid disinfectant to pro-vide reference for the reasonable application in healthcare facilities,With the continuous progress of cleaning anddisinfection technology and ir-depth expansion of application,the prospect of hypochlorous acid disinfectant appli-cation in the medical field will be broader.
Key words:Hypochlorous acid;Hypochlorous acid disinfectant; Medical institution;Physicochemical property;Disinfection
高晓东',胡必杰',鲍容3
(1.复旦大学附属中山医院感染管理科2.临床微生物试验室,上海200032)
摘要:目的探讨次氯酸对皮肤软组织感染常见病原体(包括标准茁株及临床茁株)的体外杀菌效果,为临床应用提供依据。方法﹐根抛《消毒技术规范》将0.5左氏单位的临床分离茁株菌悬液与次氯酸作用1 min和10 min,然后将作用后的液体与中和剂混合中和消毒效果,普通病原体的混合液取1.0 ml进行琼脂倾注法培养,化脓性链球菌和非结核分枝杆菌的混合液取0.1 ml分别在血平板和7H10平板上进行涂布法培养;除非结核分枝杆菌培养7d外,其他病原体培莽48h后进行融落计数,计算杀A对数值。结果﹐次氯酸作用标准開株1 min或10min均可将菌量从0.5麦氏单位(相当于107)降剑0;临床菌株包括化脓性链球菌、耐甲氧两林金黄色懒萄球菌(MRSA).耐碳青霉烯类的鲍氏不动朴菌(CRAB).耐碳青霉烯类的铜绿假弟胞菌(CRPA).耐碳青霉烯类的肺炎克需伯杆南(CRKB),脓肿分枝杆南、色分枝杆開和产气荚膜杆開也得到同样结果。结论﹐本试验首次系统全面检测次氛酸对皮肤软组织感染常见的病原体(包括非结核分枝杆開,厌氧掬,真南等)均有很好的体外杀南活性,可以作为感染伤口的局部爪药。
关键词:次氯酸;皮肤软组纠感染;病原体
中图分类号:R187文献标识码:A文章编号:I005 4529(2017)081714 03
Effectiveness of hypochlorous acid solution against common pathogens of skin and soft tissue infection in vitro
GAO Xiao-dong,HU Bi-jie,BAO Rong
(Zhongshan Hospital of Fudan University ,Shanghai 200032,China)
Abstract:ORJECTIVE To investigale the gertmicidal elficientey of hypochlorous acid solution sgainst cotutmotLpathogcns (Inucluding staudeurd strainus anud clinical strains) of skin atnud solt tissuc inlcetion in vitro.so as to provil:the bosis for improving the boctericidal effect.METHODSAccording to " technical standord for disinfection" ,acertain concentrotion of pothogens of clinical isolates wos treated with hypochlorous ocid solution for 1 min or 10 min,anud then the action of the solution anud neutralizer were tmuixeud, 1.0ml of the tuixlure of cotmtmot.puthogens was used lor agar pouring culure,0. 1 ml of the tuixlure ol Sireplococcus pyogenes anud nontuberulosismycobecterie were cultured using the cooting method in the blood plate and 7H10 plate.Unless the nontuberculo-sis mycohscteria was cultured for 7 d, the other pathogens were cultured for 48 h and the colonies were counted.RESULTS Treatment of hypochlorous acid solution for 1 min or 10 min could decrease the amount of bacte-ris from 0.5 Maxwell units (equivalent to 107) to 0.The clinical isolstes of S. pyogenes,methicillin-resistantSta phylococcus aureus (MRSA),carbepenem-resistant Acinetobacter baumannii(CRAR),carbapenem-resistantlP'seudomonas aeruginosa (CRPA),carhapenen-resistant Klebsiella pneumoniae(CRKB),Mycohacterium ab-scess ,Mycobacterium tuberculosis , and Clostridium per fringens also got the sxatme results,CONCLUISION Hypo-chlorous acid solution has good germicidal efficiency against common pethogens of skin and soft tissve infection imvittro,and it can be used as topical treatment for infected wounds.
Key words:Hypochlorous acid solution; Skin and soft tissue infection;Pathogens
伤口世界平台生态圈,以“关爱人间所有伤口患者”为愿景,连接、整合和拓展线上和线下的管理慢性伤口的资源,倡导远程、就近和居家管理慢性伤口,解决伤口专家的碎片化时间的价值创造、诊疗经验的裂变复制、和患者的就近、居家和低成本管理慢性伤口的问题。
2019广东省医疗行业协会伤口管理分会年会
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