Efficacy of green tea (Camellia sinensis Linn) 3% extract cream on improvement of striae distensae [version 1; peer review: 2 approved]

11 2月 2025
Author :  

Sartika Ayuningsih , Nelva Karmila Jusuf , Imam Budi Putra Dermatology and Venereology, University of Sumatera Utara, Medan, North Sumatra, Indonesia

V1 First published: 21 Mar 2024, 13:208 https://doi.org/10.12688/f1000research.142199.1 Latest published: 21 Mar 2024, 13:208 https://doi.org/10.12688/f1000research.142199.1

Abstract

Background

Striae distensae (SD) is a skin condition that frequently causes dermatological consultations and although asymptomatic, it may can cause itch and burning sensation. Green tea extract contains polyphenol, including flavanol, flavandiol, flavonoid, phenolic acid, amino acids and minerals which play a role in the repair of stretch marks through anti-inflammatory mechanism, increase collagen production, fibroblast proliferation, and skin hydration.

Objective

To determine the efficacy of green tea extract cream on striae

Methods

This is a pre-experimental clinical trial with a pretest-posttest design on 36 subjects with striae distensae. Diagnosis establishes through history taking and clinical evaluation. Imam Nelva Alviera (INA) score was used as SD severity before and after the application of the 3% green tea extract cream carried out at weeks 0, 2, 4, 6, and 8. Side effects and subjects’ satisfaction were also recorded. Cochran test was carried out to see the difference before and after treatment, with a pvalue <0.05 considered significant.

Results

Majority of study subjects were 18–25 years (77.8%), had history of pregnancy (75%), had a history of menarche at the age of 12 years (27.8%) and all subjects had striae alba. There was significant decrement in INA score for striae distensae (p<0.001) after eight weeks administration of 3% green tea extract cream. Clinical improvement and no side effects were also noted. All subjects were

Conclusions

The use of 3% green tea extract cream can improve the appearance of

Keywords

striae distensae, stretch mark, INA score, green tea extract, Camellia sinensis linn

 

 

 

This article is excerpted from the F1000 Research 2024, 13:208 Last updated: 06 JUN 2024 by Wound World.

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