Ademilton Costa Alves † , Sergio Murilo da Silva Braga Martins, Jr. † , José Victor Trindade Belo, Mauro Victor Castro Lemos , Carlos Emanuel de Matos Chaves Lima, Carlos Drielson da Silva, Adrielle Zagmignan and Luís Cláudio Nascimento da Silva *
Citation: Alves, A.C.; Martins, S.M.d.S.B., Jr.; Belo, J.V.T.; Lemos, M.V.C.; Lima, C.E.d.M.C.; Silva, C.D.d.; Zagmignan, A.; Nascimento da Silva, L.C. Global Trends and Scientific Impact of Topical Probiotics in Dermatological Treatment and Scientific Microorganisms 2024, 12, 2010. https://doi.org/10.3390/ microorganisms12102010 Academic Editor: Alex Galanis Received: 16 August 2024 Revised: 21 September 2024 Accepted: 24 September 2024 Published: 3 October 2024
Copyright: © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/)
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Abstract: The skin plays a crucial role in maintaining homeostasis and protecting against external ag gressors. Recent research has highlighted the potential of probiotics and postbiotics in dermatological treatments and skincare. These beneficial microorganisms interact with the skin microbiota, modulate the immune response, and enhance the skin barrier, offering a promising therapeutic avenue for various skin conditions, such as acne, dermatitis, eczema, and psoriasis. This bibliometric study aims to analyze the global trends and scientific impact of topical probiotics in dermatology. By reviewing 106 articles published between 2013 and 2023, the study categorizes the applications of probiotics in wound healing, inflammatory skin diseases, and general skincare. The findings indicate a sig nificant increase in publications from 2021 onwards, attributed to the heightened focus on medical research during the COVID-19 pandemic. This study also identifies the most productive countries, institutions, and authors in this field, highlighting the importance of international collaborations. The results underscore the efficacy of probiotic-based topical formulations in improving skin health, reducing inflammation, and enhancing wound healing. This comprehensive analysis supports the development of new therapeutic strategies based on topical probiotics and encourages high-quality research in this promising area.
Keywords: topical probiotics; skin microbiome; wound healing; inflammatory skin diseases; skin care
Amy Forman Taub1,2 *
1 Institute Advanced Dermatology, A Forefront Dermatology Practice, Lincolnshire, IL, United States,
2 Department of Dermatology, Institute Northwestern University Medical School, Chicago, IL, United States
OPEN ACCESS EDITED BY Saranya Wyles, Mayo Clinic, United States REVIEWED BY Alessandra Magenta, Consiglio Nazionale delle Ricerche (CNR), Italy Krishna Vyas, Massachusetts General Hospital and Harvard Medical School, United States *CORRESPONDENCE Amy Forman Taub 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 RECEIVED 04 June 2024 ACCEPTED 20 August 2024 PUBLISHED 15 October 2024 CITATION Taub AF (2024) Regenerative topical skincare: stem cells and exosomes. Front. Med. 11:1443963. doi: 10.3389/fmed.2024.1443963 COPYRIGHT
© 2024 Taub. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Regenerative medicine and its offshoot, regenerative aesthetics, have been hot topics over the past 15 years. Studies with heterochronic parabiosis and others pointed to a circulating factor that could rejuvenate aging tissues. Stem cells are known to have regenerative powers, but they are difficult to extract, grow in culture or maintain. Exosomes (EVs), extracellular vesicles from 30 to 150 nm, have been discovered to be a primary form of communication between tissues. Using stem cell supernatants to generate desirable EVs has become a heralded treatment for aesthetic treatments. Preclinical studies with EVs show many benefits including improving the function of fibroblasts and healing wounds more rapidly. Clinical studies with EVs in aesthetics are very few. Thus, the excitement generated by EVs should be tempered with realism about the lack of available treatment products as well as the lack of scientific proof.
KEYWORDS skin, aesthetic, regenerative, stem cells, exosomes
原创：卢魁
我们经常能看到些步履蹒跚的老年人和些行动不便的中年人， 他们与那些行色匆匆的年轻人形成了鲜明的对比，这些老年人中有一半以上都会受着各种各样的疾病困扰，而最常见的一种就“慢性伤口”。
原创:卢魁
少吃多尝：宴席上丰盛的四高膳食对糖尿病病情控制十分不利，不少糖尿病病人觉得赴宴后血糖会有所升高，所以糖尿病惠者饮食必须控制总热量，一般以低热量、低脂肪、低糖、高纤维膳食为主。面对宴席上的“四高”食品多尝，以免一吃就超量，要像靖蜓点水一样多样化地品尝一点，选择性地少吃一些。这样既饱了口福，也不至于超量。
原创：祝建清
生活中难免磕磕碰碰，跌跌撞撞受伤之后该如何处理伤口呢？红药水、碘酒……这些家庭常备药物看着都眼熟但你分得清什么伤口用什么药吗？处理伤口，药水选哪种好？
伤口世界平台生态圈，以“关爱人间所有伤口患者”为愿景，连接、整合和拓展线上和线下的管理慢性伤口的资源，倡导远程、就近和居家管理慢性伤口，解决伤口专家的碎片化时间的价值创造、诊疗经验的裂变复制、和患者的就近、居家和低成本管理慢性伤口的问题。
2019广东省医疗行业协会伤口管理分会年会
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