Kyu-Il Lee1 , Yu-Kyeong Yun2 , Seung-Kyu Han2,3 , Kyung-Chul Moon2,3 , Sik Namgoong2,3 ,
Seong-Ho Jeong3 , Eun-Sang Dhong3
1Department of Plastic Surgery, Taean Public Health Office, Taean, Korea
2Diabetic Wound Center and Department of Plastic Surgery, Korea University Guro Hospital, Seoul, Korea
3Department of Plastic Surgery, Korea University College of Medicine, Seoul, Korea
Abstract
Background: Adequate tissue oxygenation is a key determinant of diabetic foot ulcer (DFU) outcomes. Though transcutaneous oxygen pressure (TcPO2) is the gold standard for evaluating tissue oxygenation, its limited availability restricts routine clinical use. Consequently, toe pressure is frequently utilized as a practical surrogate; however, the direct correlation between these two modalities has yet to be rigorously investigated. This study aimed to assess the correlation and agreement between TcPO2and toe pressure in patients with DFUs.
Methods: A retrospective review was conducted on 837 DFU patients who received simultaneous TcPO2and toe pressure assessments.
The correlation between the two tests was analyzed using the Pearson correlation coefficient, and agreement was evaluated using Bland– Altman analysis. To aid interpretation, a scatterplot and Bland–Altman plot were generated.
Results: TcPO2and toe pressure demonstrated a strong correlation (R=0.66; 95% confidence interval, 0.62 to 0.70; P<0.001). Bland–
Altman analysis showed a mean bias of 26.9 mmHg (standard deviation of differences, 28.8 mmHg; 95% limits of agreement, −28.9 to 82.6 mmHg) between toe pressure and TcPO2, reflecting limited agreement and increased variability at higher perfusion levels.
Conclusion: TcPO2and toe pressure are strongly correlated. However, they are not interchangeable, particularly in DFU patients with high tissue perfusion.
Keywords: Diabetic foot; Foot ulcer; Ischemia; Microcirculation
本文转载于J Clin Aesthet Dermatol. 2018;11(11):36–39，不代表本网站赞同其观点和对其真实性负责，我们只作于阅读分享，非商业用途，如若侵权，请告知删除。
his article is excerpted from the《Journal of Cosmetic Dermatology》by Wound World
This article is excerpted from the 《Small Science》 by Wound World
伤口世界平台生态圈，以“关爱人间所有伤口患者”为愿景，连接、整合和拓展线上和线下的管理慢性伤口的资源，倡导远程、就近和居家管理慢性伤口，解决伤口专家的碎片化时间的价值创造、诊疗经验的裂变复制、和患者的就近、居家和低成本管理慢性伤口的问题。
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