A.Giaccari1 · G. Gliozzo1 · G. Ciccarelli1 · G. Di Giuseppe1 · C. Castellano2 · S. Cum3 · L. Delle Monache4,13 · M. Gallo5 ·M.Lastretti6 · G. Medea7 · M. Monesi8 · R. Napoli9 · B. Pintaudi10 · E. Succurro11 · G. Turchetti
Received: 9 January 2026 / Accepted: 17 March 2026 © The Author(s) 2026
Abstract
Background and aims Although continuous glucose monitoring (CGM) devices are now standard of care among Type 1 diabetes patients, they are still relatively underutilized in Type 2 diabetes (T2D), particularly in those patients not treated with insulin. Widespread adoption continues to be hindered by a combination of factors. Chief among these is the scarcity of long-term, large-scale clinical trials demonstrating the benefits of the use of CGM in T2D. This meta-analysis aimed to address this gap by comparing CGM with self-blood glucose monitoring (SBMG), with primary outcomes of HbA1c and time in range (TIR) in insulin-treated and non-insulin-treated TD2 patients.
Methods and results Following the stringent rules mandated by our National Health Service (which requires a panel com-posed of all stakeholders involved in diabetes treatment, and includes PICO, GRADE, AGREE, and meta-analyses), we performed a systematic review of RCTs that enrolled two groups of individuals with T2D, those treated with insulin (includ-ing basal and basal-bolus regimens), and those receiving treatments other than insulin. All included trials compared CGM with structured blood glucose monitoring (SBGM) with glycated hemoglobin (HbA1c) as the main endpoint. Based on the strength and consistency of the evidence, the panel issued a strong recommendation in favor of CGM for individuals with T2D treated with insulin (including those on basal insulin alone) and for individuals with T2D not treated with insulin, par-ticularly for those with glycated hemoglobin levels≥7%. From a pharmacoeconomic perspective, outcomes were positive in both patient groups.
Conclusion CGM represents a clinically effective and cost-efficient approach to optimizing glycemic control in T2D, becom-ing mandatory among individuals on insulin therapy. Our findings support a shift in clinical practice toward the more widespread use of CGM in T2D, with regulatory frameworks and reimbursement policies needing to adapt accordingly.
Keywords CGM · Type 2 Diabetes · Metanalysis · PICO · GRADE · Guidelines
Communicated by Massimo Federici, M.D.
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1 Center for Endocrine and Metabolic Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS and Università Cattolica del Sacro Cuore, Rome, Italy
2 Azienda USL of Modena, Sassuolo Hospital, Sassuolo, Italy
3 Diabetes and Diabetic Foot Care Unit, ASUGI, Monfalcone, Italy
4 National Board Member of FAND (Italian Association for the Rights of Diabetic People), Roma, Italy
5 Department of Endocrinology and Metabolic Diseases, AO SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy
6 Order of Psychologists of Lazio, Rome, Italy
7 Italian Society of General Medicine (SIMG), Florence, Italy
8 Territorial Diabetology Unit, AUSL Ferrara, Ferrara, Italy
9 Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy
10 Diabetes Unit, Niguarda Cà Granda Hospital, Milan, Italy
11 Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy
12 Institute of Management, Scuola Superiore Sant’Anna, Pisa, Italy
13 Patient Advocacy Lab, ALTEMS – Università Cattolica del Sacro Cuore, Rome, Italy
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引用本文:简喜超, 简扬, 邓呈亮. 2025版《中国糖尿病足防治实践指南》解读[J]. 中华医学美学美容杂志, 2026, 32(2): 99-103. DOI: 10.3760/cma.j.cn114657-20251215-00266.
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Authors: Rhidian Morgan-Jones (Chair), Amit Gefen and Kylie Sandy-Hodgett
Rhidian Morgan-Jones (Chair) is Consultant Orthopaedic Surgeon, Cardiff Knee Clinic, University Hospital Llandough, Cardiff, UK; Amit Gefen is Professor of Biomedical Engineering and the Herbert J. Berman Chair in Vascular Bioengineering, Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel; Kylie Sandy-Hodgetts is Associate Professor, Centre of Molecular Medicine & Innovative Therapeutics, Murdoch University; Senior Research Fellow, Director Skin Integrity Research Institute, School of Biomedical Sciences, University of Western Australia, Perth, Australia
This meeting report is based on the Mölnlycke-sponsored workshop held at the sixth World Union of Wound Healing Societies (WUWHS) Congress on March 1–5, 2022, in Abu Dhabi, United Arab Emirates. The workshop, titled ‘Surgical incision care — negative pressure wound therapy and advanced dressings: what to use and when’, included presentations from Kylie SandyHodgetts, Rhidian Morgan-Jones and Amit Gefen. The topics of surgical dressings, risk assessment and requirements of closed-incision negative pressure wound therapy (ciNPWT) were all explored.
Authors: Harikrishna KR Nair, Sylvia SY Chong, Mohd Hasbullah Bin Husain
Abstact: Negative pressure wound therapy (NPWT), is a wound dressing system that continuously or intermittently applies subatmospheric pressure to the surface of the wound, and provides a positive pressure to the surface of the wound to aid healing. The aim of this study was to assess the healing of chronic wounds treated by single-use NPWT. Study participants were selected by simple random sampling from a pool of patients who were attending their routine follow-up visits in Wound Care Unit in Hospital Kuala Lumpur. During each dressing change, the wound was assessed and cleansed with distilled water. Debridement was performed as necessary. The application of NPWT was a simple 3-steps procedure, removing the release paper from the dressing and positioning it over the wound bed, connecting the tubing from the pump to the dressing and providing negative pressure treatment through the swing. There were five patients with chronic wounds of various size and aetiologies, including a two pressure ulcers/injury (PU), two carbuncles and post-motor-vehicle accident wound, enrolled in the study, all showed complete wound healing. The two abscesses healed on week 6 and 8 with the single use NPWT and the traumatic wound healed in 10 weeks. Both the sacral and gluteal PUs healed on week 28 and week 14. Case 3, the gluteal PU, healed at week 14 due to the good standard of care, 2-hourly repositioning, proper support surface and good nutritional diet. Meanwhile, the sacral PU took double the time i.e. 28 weeks as the wound area is larger and poor adherence to standard of care. NPWT pressure between −75 and −125mmHg would provide moist environment that is suitable for wound healing. It aids healing by improving the rate of angiogenesis, endothelial proliferation, capillary blood flow, reducing oedema and bacterial burden within the wound. The limitation of this study was the small number of patients and might not represent the population at large. A much larger study would be needed to show the significance of these findings.
Key words: ■ Chronic wounds ■ Negative pressure wound therapy (NPWT) ■ Pressure ulcer ■ Wound healing
Prevention and appropriate management of wound infection is central to promote the healing process. While not all wounds will necessitate use of systemic antibiotics, some may benefit from the use of topical antimicrobials as part of a holistic standard of care. This article describes five different cases, from China, where the clinicians used Technology Lipido-Colloid Silver Non-Adherent (TLC-Ag) dressings as part of their holistic multidisciplinary wound management strategy. The wounds discussed were mainly chronic, including two venous leg ulcers and lymphoedema ulcer, a post-amputation wound as well as a case of pyoderma gangrenosum. Managing these wounds with TLC-Ag as a part of the standard holistic multidisciplinary care provided resulted in positive outcomes for the patients.
Key words: ■ Acute wounds . ■ Chronic wounds . ■ Silver antimicrobial . ■ UrgoTul Ag . ■ Wound infection
Foot complications from diabetes mellitus are one of main causes of lower limb amputation, however, public awareness of diabetic foot care is low. A mobile app “Happy Feet” was developed,s targeting patients with diabetic foot ulcers (DFU). Patients foot awareness substantially increased after three and six months of using the application. Mean total scores between baseline and three months were significantly increased (baseline versus three months, 22.80 versus 25.54; p<0.01), and between three and six months in “examining between the toes” and “breaking in new shoes slowly” (p<0.01). Policymakers and medical professionals benefit from the mobile app by providing accurate and precise information from this group of patients.
Key words: Diabetic foot 、Mobile phone application 、 Self-care 、 Self-assessment
Hard-to-heal wounds are challenging to treat and the associated costs consistently fall on outpatient, community and home care budgets. There is a growing body of evidence that suggests the use of PICO™ single-use negative pressure wound therapy (sNPWT) can potentially help improve healing rates of wounds that are deemed as not healing and reduce associated nursing resources and costs. A 323-patient service evaluation was conducted across 17 sites in Denmark, Ireland, Sweden and the United Kingdom between 2016 and 2022. The results are presented in this article.
Authors:
Jane Hampton, Helen Meagher, Andrew Sharpe, Tim Styche and Jacqui Hughes
Jane Hampton is a Wound Consultant in Aarhus, Denmark; Helen Meagheris a Registered Advanced Nurse Practitioner in Tissue Viability, Ireland; Andrew Sharpe is Advanced Podiatrist, Salford Care Organisation, Part of the Northern Care Alliance, UK; Tim Styche is Market Access & Healthcare Economics Manager at Smith+Nephew; Jacqui Hughes is Senior Healthcare Outcomes Manager at Smith+Nephew
Chronic wounds with low healing rate generally lead to decreased in quality of life of patients, financial burden and increased morbidity rate (Järbrink et al, 2016). Thus, wound care management involving a patented 4-in-1 formulation is an aid in the management of chronic wounds. To demonstrate its efficacy, seven patients were chosen, four with a venous leg ulcer, two with a diabetic foot ulcer and 1 with a pressure ulcer. All the wounds were cleaned, debrided and then the silicon dioxide, silver ions, chlorhexidine and hyaluronic acid cream (KAdermin cream) was applied as the primary dressing, with a non-adhesive dressing as a secondary dressing. This case series demonstrates that the cream was able to reduce wound size significantly, while eliminating infection signs.
Harikrishna KR Nair is a Professor and Head of Wound Care Unit, Department of Internal Medicine, Hospital Kuala Lumpur; Nur Zati Ilwani, a SRN, Staff Nurse of Wound Care Unit, Department of Internal Medicine, Hospital Kuala Lumpur; Ling Li Ng is a Pharmacist of Y.S.P. Industries (M) Sdn. Bhd.Lumpur
伤口世界平台生态圈,以“关爱人间所有伤口患者”为愿景,连接、整合和拓展线上和线下的管理慢性伤口的资源,倡导远程、就近和居家管理慢性伤口,解决伤口专家的碎片化时间的价值创造、诊疗经验的裂变复制、和患者的就近、居家和低成本管理慢性伤口的问题。
2019广东省医疗行业协会伤口管理分会年会
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