文献精选

四肢骨与软组织肿瘤术后伤口保养8个建议！

原创：沈宇辉骨科在线orthonline

来源：上海交通大学医学院附属瑞金医院沈宇辉

虽然外科手术后伤口问题愈合基本类似，但是腹部、颈部、胸部、背部和四肢的骨与软组织肿瘤术后的伤口愈合还是有区别的。

浅谈伤口冲洗

医学生

来源：慢伤前沿（ID：woundexpert）

伤口冲洗是一种被广泛应用的治疗手段，在伤口管理中发挥着很重要的作用，可以水化伤口、去除深部碎屑和协助医护人员更好地检查伤口。冲洗液可以去除细胞碎屑和表面微生物或残留局部药物和敷料。与棉签擦拭或浸浴相比，伤口冲洗能更有效地清洁伤口。

局部评估，将“复杂”的伤口简单化

原创：张培洁中国护理管理

探案：心脏手术2年多，反复伤口渗脓和面部皮疹为哪般？

原创：黄英男、金文婷等 SIFIC感染官微

作者：黄英男金文婷马玉燕

审阅：胡必杰潘珏

第269页共434页

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Global Trends and Scientific Impact of Topical Probiotics in Dermatological Treatment and Skincare 2025-08-18 00:00

Ademilton Costa Alves † , Sergio Murilo da Silva Braga Martins, Jr. † , José Victor Trindade Belo, Mauro Victor Castro Lemos , Carlos Emanuel de Matos Chaves Lima, Carlos Drielson da Silva, Adrielle Zagmignan and Luís Cláudio Nascimento da Silva *

Citation: Alves, A.C.; Martins, S.M.d.S.B., Jr.; Belo, J.V.T.; Lemos, M.V.C.; Lima, C.E.d.M.C.; Silva, C.D.d.; Zagmignan, A.; Nascimento da Silva, L.C. Global Trends and Scientific Impact of Topical Probiotics in Dermatological Treatment and Scientific Microorganisms 2024, 12, 2010. https://doi.org/10.3390/ microorganisms12102010 Academic Editor: Alex Galanis Received: 16 August 2024 Revised: 21 September 2024 Accepted: 24 September 2024 Published: 3 October 2024

Copyright: © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/)

Laboratório de Patogenicidade Microbiana, Universidade CEUMA, São Luis 65075-120, MA, Brazil; 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 (A.C.A.); 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 (S.M.d.S.B.M.J.); 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 (J.V.T.B.); 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 (M.V.C.L.); 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 (C.E.d.M.C.L.); 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 (C.D.d.S.); 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 (A.Z.) * Correspondence: 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。; Tel.: +55-(98)-9-8431-8133 † These authors contributed equally to this work.

Abstract: The skin plays a crucial role in maintaining homeostasis and protecting against external ag gressors. Recent research has highlighted the potential of probiotics and postbiotics in dermatological treatments and skincare. These beneficial microorganisms interact with the skin microbiota, modulate the immune response, and enhance the skin barrier, offering a promising therapeutic avenue for various skin conditions, such as acne, dermatitis, eczema, and psoriasis. This bibliometric study aims to analyze the global trends and scientific impact of topical probiotics in dermatology. By reviewing 106 articles published between 2013 and 2023, the study categorizes the applications of probiotics in wound healing, inflammatory skin diseases, and general skincare. The findings indicate a sig nificant increase in publications from 2021 onwards, attributed to the heightened focus on medical research during the COVID-19 pandemic. This study also identifies the most productive countries, institutions, and authors in this field, highlighting the importance of international collaborations. The results underscore the efficacy of probiotic-based topical formulations in improving skin health, reducing inflammation, and enhancing wound healing. This comprehensive analysis supports the development of new therapeutic strategies based on topical probiotics and encourages high-quality research in this promising area.

Keywords: topical probiotics; skin microbiome; wound healing; inflammatory skin diseases; skin care
Regenerative topical skincare: stem cells and exosomes 2025-08-15 00:00

Amy Forman Taub1,2 *

1 Institute Advanced Dermatology, A Forefront Dermatology Practice, Lincolnshire, IL, United States,

2 Department of Dermatology, Institute Northwestern University Medical School, Chicago, IL, United States

OPEN ACCESS EDITED BY Saranya Wyles, Mayo Clinic, United States REVIEWED BY Alessandra Magenta, Consiglio Nazionale delle Ricerche (CNR), Italy Krishna Vyas, Massachusetts General Hospital and Harvard Medical School, United States *CORRESPONDENCE Amy Forman Taub 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 RECEIVED 04 June 2024 ACCEPTED 20 August 2024 PUBLISHED 15 October 2024 CITATION Taub AF (2024) Regenerative topical skincare: stem cells and exosomes. Front. Med. 11:1443963. doi: 10.3389/fmed.2024.1443963 COPYRIGHT

© 2024 Taub. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

Regenerative medicine and its offshoot, regenerative aesthetics, have been hot topics over the past 15 years. Studies with heterochronic parabiosis and others pointed to a circulating factor that could rejuvenate aging tissues. Stem cells are known to have regenerative powers, but they are difficult to extract, grow in culture or maintain. Exosomes (EVs), extracellular vesicles from 30 to 150 nm, have been discovered to be a primary form of communication between tissues. Using stem cell supernatants to generate desirable EVs has become a heralded treatment for aesthetic treatments. Preclinical studies with EVs show many benefits including improving the function of fibroblasts and healing wounds more rapidly. Clinical studies with EVs in aesthetics are very few. Thus, the excitement generated by EVs should be tempered with realism about the lack of available treatment products as well as the lack of scientific proof.

KEYWORDS skin, aesthetic, regenerative, stem cells, exosomes
Can a 19th Century French Medical Debate Provide Guidance on How to Tackle Type 2 Diabetes? 2025-08-14 00:00

Abdo S. Yazbeck

To cite this article: Abdo S. Yazbeck (2025) Can a 19th Century French Medical Debate Provide Guidance on How to Tackle Type 2 Diabetes?, Health Systems & Reform, 11:1, 2464977, DOI: 10.1080/23288604.2025.2464977

To link to this article: https://doi.org/10.1080/23288604.2025.2464977

© 2025 The Author(s). Published with license by Taylor & Francis Group, LLC.

Published online: 25 Feb 2025.

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© 2025 The Author(s). Published with license by Taylor & Francis Group, LLC.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

ARTICLE HISTORY Received 24 November 2024; Revised 1 February 2025; Accepted 5 February 2025

KEYWORDS Health systems; type 2 diabetes; non-communicable diseases; germ theory of disease

Custom Mod Mega1

主任医师、教授、博导，南方医科大学第三附属医院（广东省骨科医院）院长

文献精选

四肢骨与软组织肿瘤术后伤口保养8个建议！

原创：沈宇辉骨科在线orthonline

浅谈伤口冲洗

医学生

局部评估，将“复杂”的伤口简单化

原创：张培洁中国护理管理

探案：心脏手术2年多，反复伤口渗脓和面部皮疹为哪般？

原创：黄英男、金文婷等 SIFIC感染官微

学术会议

伤口世界提示

Custom Mod Mega1

主任医师、教授、博导，南方医科大学第三附属医院（广东省骨科医院）院长

文献精选

四肢骨与软组织肿瘤术后伤口保养8个建议！

原创： 沈宇辉 骨科在线orthonline

浅谈伤口冲洗

医学生

局部评估，将“复杂”的伤口简单化

原创： 张培洁 中国护理管理

探案：心脏手术2年多，反复伤口渗脓和面部皮疹为哪般？

原创： 黄英男、金文婷等 SIFIC感染官微

消息订阅

学术会议

伤口世界提示

原创：沈宇辉骨科在线orthonline

原创：张培洁中国护理管理

原创：黄英男、金文婷等 SIFIC感染官微