文献精选

糖尿病日科普：正确预防糖尿病足，远离截肢！

胡海涛负压引流与创面修复

联合国糖尿病日前身是世界糖尿病日（World Diabetes Day' WDD），由世界卫生组织和国际糖尿病联盟于1991年共同发起的，其宗旨是引起全球对糖尿病的警觉和醒悟。

破伤风，伤口工作中需要知道的知识点儿（上篇基础理论）

文章转自公众号：迷途小羔羊9527

这段时间准备给学生讲课，其中一个内容就是破伤风。这个病在11年前实习的时候管过一例（暴露年龄了），之后就没接触过。快要讲课了，心里有点虚，找资料来恶补一轮，也就顺便更新一下，就当预讲课。

关爱癌性伤口患者，努力让他们活得更有尊严

原创：胡海涛负压引流与创面修复

癌性伤口，给患者的伤痛难于安抚，他们活在癌症与伤口疼痛双重压力下，连正常洗澡权力可能被剥夺了，是苦不堪言。

过去处理过颈部巨大癌性溃疡、会阴部巨大溃疡、腹部癌性肠瘘，虽然没能把他们治愈，但是通过专业处理，他们在离世之前获得了最后的尊严。

7天治愈颈部脓肿——从切开到愈合！

原创：胡海涛负压引流与创面修复

女性患者，29岁，因为害怕手术，颈部包块肿痛1月，一直保守治疗，超声示左侧颈前区脓肿，一周后需要出国旅游，提出‘一周可以治愈吗’？

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Global Trends and Scientific Impact of Topical Probiotics in Dermatological Treatment and Skincare 2025-08-18 00:00

Ademilton Costa Alves † , Sergio Murilo da Silva Braga Martins, Jr. † , José Victor Trindade Belo, Mauro Victor Castro Lemos , Carlos Emanuel de Matos Chaves Lima, Carlos Drielson da Silva, Adrielle Zagmignan and Luís Cláudio Nascimento da Silva *

Citation: Alves, A.C.; Martins, S.M.d.S.B., Jr.; Belo, J.V.T.; Lemos, M.V.C.; Lima, C.E.d.M.C.; Silva, C.D.d.; Zagmignan, A.; Nascimento da Silva, L.C. Global Trends and Scientific Impact of Topical Probiotics in Dermatological Treatment and Scientific Microorganisms 2024, 12, 2010. https://doi.org/10.3390/ microorganisms12102010 Academic Editor: Alex Galanis Received: 16 August 2024 Revised: 21 September 2024 Accepted: 24 September 2024 Published: 3 October 2024

Copyright: © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/)

Laboratório de Patogenicidade Microbiana, Universidade CEUMA, São Luis 65075-120, MA, Brazil; 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 (A.C.A.); 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 (S.M.d.S.B.M.J.); 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 (J.V.T.B.); 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 (M.V.C.L.); 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 (C.E.d.M.C.L.); 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 (C.D.d.S.); 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 (A.Z.) * Correspondence: 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。; Tel.: +55-(98)-9-8431-8133 † These authors contributed equally to this work.

Abstract: The skin plays a crucial role in maintaining homeostasis and protecting against external ag gressors. Recent research has highlighted the potential of probiotics and postbiotics in dermatological treatments and skincare. These beneficial microorganisms interact with the skin microbiota, modulate the immune response, and enhance the skin barrier, offering a promising therapeutic avenue for various skin conditions, such as acne, dermatitis, eczema, and psoriasis. This bibliometric study aims to analyze the global trends and scientific impact of topical probiotics in dermatology. By reviewing 106 articles published between 2013 and 2023, the study categorizes the applications of probiotics in wound healing, inflammatory skin diseases, and general skincare. The findings indicate a sig nificant increase in publications from 2021 onwards, attributed to the heightened focus on medical research during the COVID-19 pandemic. This study also identifies the most productive countries, institutions, and authors in this field, highlighting the importance of international collaborations. The results underscore the efficacy of probiotic-based topical formulations in improving skin health, reducing inflammation, and enhancing wound healing. This comprehensive analysis supports the development of new therapeutic strategies based on topical probiotics and encourages high-quality research in this promising area.

Keywords: topical probiotics; skin microbiome; wound healing; inflammatory skin diseases; skin care
Regenerative topical skincare: stem cells and exosomes 2025-08-15 00:00

Amy Forman Taub1,2 *

1 Institute Advanced Dermatology, A Forefront Dermatology Practice, Lincolnshire, IL, United States,

2 Department of Dermatology, Institute Northwestern University Medical School, Chicago, IL, United States

OPEN ACCESS EDITED BY Saranya Wyles, Mayo Clinic, United States REVIEWED BY Alessandra Magenta, Consiglio Nazionale delle Ricerche (CNR), Italy Krishna Vyas, Massachusetts General Hospital and Harvard Medical School, United States *CORRESPONDENCE Amy Forman Taub 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。 RECEIVED 04 June 2024 ACCEPTED 20 August 2024 PUBLISHED 15 October 2024 CITATION Taub AF (2024) Regenerative topical skincare: stem cells and exosomes. Front. Med. 11:1443963. doi: 10.3389/fmed.2024.1443963 COPYRIGHT

© 2024 Taub. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

Regenerative medicine and its offshoot, regenerative aesthetics, have been hot topics over the past 15 years. Studies with heterochronic parabiosis and others pointed to a circulating factor that could rejuvenate aging tissues. Stem cells are known to have regenerative powers, but they are difficult to extract, grow in culture or maintain. Exosomes (EVs), extracellular vesicles from 30 to 150 nm, have been discovered to be a primary form of communication between tissues. Using stem cell supernatants to generate desirable EVs has become a heralded treatment for aesthetic treatments. Preclinical studies with EVs show many benefits including improving the function of fibroblasts and healing wounds more rapidly. Clinical studies with EVs in aesthetics are very few. Thus, the excitement generated by EVs should be tempered with realism about the lack of available treatment products as well as the lack of scientific proof.

KEYWORDS skin, aesthetic, regenerative, stem cells, exosomes
Can a 19th Century French Medical Debate Provide Guidance on How to Tackle Type 2 Diabetes? 2025-08-14 00:00

Abdo S. Yazbeck

To cite this article: Abdo S. Yazbeck (2025) Can a 19th Century French Medical Debate Provide Guidance on How to Tackle Type 2 Diabetes?, Health Systems & Reform, 11:1, 2464977, DOI: 10.1080/23288604.2025.2464977

To link to this article: https://doi.org/10.1080/23288604.2025.2464977

© 2025 The Author(s). Published with license by Taylor & Francis Group, LLC.

Published online: 25 Feb 2025.

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© 2025 The Author(s). Published with license by Taylor & Francis Group, LLC.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

ARTICLE HISTORY Received 24 November 2024; Revised 1 February 2025; Accepted 5 February 2025

KEYWORDS Health systems; type 2 diabetes; non-communicable diseases; germ theory of disease

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主任医师、教授、博导，南方医科大学第三附属医院（广东省骨科医院）院长

文献精选

糖尿病日科普：正确预防糖尿病足，远离截肢！

破伤风，伤口工作中需要知道的知识点儿（上篇基础理论）

关爱癌性伤口患者，努力让他们活得更有尊严

7天治愈颈部脓肿——从切开到愈合！

学术会议

伤口世界提示

Custom Mod Mega1

主任医师、教授、博导，南方医科大学第三附属医院（广东省骨科医院）院长

文献精选

糖尿病日科普：正确预防糖尿病足，远离截肢！

破伤风，伤口工作中需要知道的知识点儿（上篇基础理论）

关爱癌性伤口患者，努力让他们活得更有尊严

7天治愈颈部脓肿——从切开到愈合！

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