Kyu-Il Lee1 , Yu-Kyeong Yun2 , Seung-Kyu Han2,3 , Kyung-Chul Moon2,3 , Sik Namgoong2,3 ,
Seong-Ho Jeong3 , Eun-Sang Dhong3
1Department of Plastic Surgery, Taean Public Health Office, Taean, Korea
2Diabetic Wound Center and Department of Plastic Surgery, Korea University Guro Hospital, Seoul, Korea
3Department of Plastic Surgery, Korea University College of Medicine, Seoul, Korea
Abstract
Background: Adequate tissue oxygenation is a key determinant of diabetic foot ulcer (DFU) outcomes. Though transcutaneous oxygen pressure (TcPO2) is the gold standard for evaluating tissue oxygenation, its limited availability restricts routine clinical use. Consequently, toe pressure is frequently utilized as a practical surrogate; however, the direct correlation between these two modalities has yet to be rigorously investigated. This study aimed to assess the correlation and agreement between TcPO2and toe pressure in patients with DFUs.
Methods: A retrospective review was conducted on 837 DFU patients who received simultaneous TcPO2and toe pressure assessments.
The correlation between the two tests was analyzed using the Pearson correlation coefficient, and agreement was evaluated using Bland– Altman analysis. To aid interpretation, a scatterplot and Bland–Altman plot were generated.
Results: TcPO2and toe pressure demonstrated a strong correlation (R=0.66; 95% confidence interval, 0.62 to 0.70; P<0.001). Bland–
Altman analysis showed a mean bias of 26.9 mmHg (standard deviation of differences, 28.8 mmHg; 95% limits of agreement, −28.9 to 82.6 mmHg) between toe pressure and TcPO2, reflecting limited agreement and increased variability at higher perfusion levels.
Conclusion: TcPO2and toe pressure are strongly correlated. However, they are not interchangeable, particularly in DFU patients with high tissue perfusion.
Keywords: Diabetic foot; Foot ulcer; Ischemia; Microcirculation
本文转载于J Clin Aesthet Dermatol. 2018;11(11):36–39,不代表本网站赞同其观点和对其真实性负责,我们只作于阅读分享,非商业用途,如若侵权,请告知删除。
原创: 十六点五 中山二院糖尿病足中心
糖尿病足部的慢性溃疡是否存在感染,好像应该是没有多少疑问的,但在所谓的“神经性溃疡”的表面是否存在有临床意义的感染,一直有争议。
对于外周血管病变的介入治疗,较IWGDF指南较有关OFFLOADING的细节描述,有关介入治疗的部分实在是比较粗慥,目前糖尿病外周血管病变介入治疗的热点问题大部分都没有涉及
对于糖尿病外周血管病变的治疗,2019年版IWGDF指南讲的比较少,无论是内科治疗还是介入治疗,这版的指南都讲得比较少(其实之前版本的IWGDF指南有关血管病变方面的内容更少),而国内糖尿病足指南,提到有关糖尿病外周血管病变治疗,一般都会用比较大的篇幅谈到其内科治疗。
人们对于糖尿病外周血管病变越来越关注,一方面,它是糖尿病足形成的最重要的原因;另一方面,它也是糖尿病进展到一定程度的标志,严重的糖尿病外周血管病变,往往标志着糖尿病进展到晚期,心、肾、脑、眼底等重要脏器的血管也存在严重的问题,而糖尿病足长期的皮肤溃疡不愈合,其产生的大量炎症因子,也会加重这些血管病变,因此,如何评价(诊断)及治疗糖尿病外周血管病变,成为了糖尿病诊断和治疗的最重要的领域。
伤口世界平台生态圈,以“关爱人间所有伤口患者”为愿景,连接、整合和拓展线上和线下的管理慢性伤口的资源,倡导远程、就近和居家管理慢性伤口,解决伤口专家的碎片化时间的价值创造、诊疗经验的裂变复制、和患者的就近、居家和低成本管理慢性伤口的问题。
2019广东省医疗行业协会伤口管理分会年会
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