Kyu-Il Lee1 , Yu-Kyeong Yun2 , Seung-Kyu Han2,3 , Kyung-Chul Moon2,3 , Sik Namgoong2,3 ,
Seong-Ho Jeong3 , Eun-Sang Dhong3
1Department of Plastic Surgery, Taean Public Health Office, Taean, Korea
2Diabetic Wound Center and Department of Plastic Surgery, Korea University Guro Hospital, Seoul, Korea
3Department of Plastic Surgery, Korea University College of Medicine, Seoul, Korea
Abstract
Background: Adequate tissue oxygenation is a key determinant of diabetic foot ulcer (DFU) outcomes. Though transcutaneous oxygen pressure (TcPO2) is the gold standard for evaluating tissue oxygenation, its limited availability restricts routine clinical use. Consequently, toe pressure is frequently utilized as a practical surrogate; however, the direct correlation between these two modalities has yet to be rigorously investigated. This study aimed to assess the correlation and agreement between TcPO2and toe pressure in patients with DFUs.
Methods: A retrospective review was conducted on 837 DFU patients who received simultaneous TcPO2and toe pressure assessments.
The correlation between the two tests was analyzed using the Pearson correlation coefficient, and agreement was evaluated using Bland– Altman analysis. To aid interpretation, a scatterplot and Bland–Altman plot were generated.
Results: TcPO2and toe pressure demonstrated a strong correlation (R=0.66; 95% confidence interval, 0.62 to 0.70; P<0.001). Bland–
Altman analysis showed a mean bias of 26.9 mmHg (standard deviation of differences, 28.8 mmHg; 95% limits of agreement, −28.9 to 82.6 mmHg) between toe pressure and TcPO2, reflecting limited agreement and increased variability at higher perfusion levels.
Conclusion: TcPO2and toe pressure are strongly correlated. However, they are not interchangeable, particularly in DFU patients with high tissue perfusion.
Keywords: Diabetic foot; Foot ulcer; Ischemia; Microcirculation
本文转载于J Clin Aesthet Dermatol. 2018;11(11):36–39,不代表本网站赞同其观点和对其真实性负责,我们只作于阅读分享,非商业用途,如若侵权,请告知删除。
原创:十六点五 中山二院糖尿病足中心
糖尿病足中有一种类型令人十分头疼,就是老人、干性坏疽、十分疼痛(静息疼痛,每到晚上患者都痛得喊“妈”),其实这种病人就是由于糖尿病外周血管病变为主要病因导致的糖尿病足。
原创:十六点五 中山二院糖尿病足中心
糖尿病足是一种顽症,讲到底就是糖尿病人足部伤口难以愈合,而一般皮肤溃疡的愈合都是疤痕愈合,疤痕愈合最重要的原料就是胶原蛋白,因此,糖尿病足难以愈合最重要的直接原因就是在糖尿病的状态下,足部皮肤溃疡的胶原蛋白生成少、慢、质量差。
糖尿病足以变化多端,治疗效果差,治疗方法多而成为一种难治性疾病。经过近20年的反复临床摸索,我们中心逐步形成了一整套对于大部分糖尿病足都行之有效的局部治疗方法。
伤口世界平台生态圈,以“关爱人间所有伤口患者”为愿景,连接、整合和拓展线上和线下的管理慢性伤口的资源,倡导远程、就近和居家管理慢性伤口,解决伤口专家的碎片化时间的价值创造、诊疗经验的裂变复制、和患者的就近、居家和低成本管理慢性伤口的问题。
2019广东省医疗行业协会伤口管理分会年会
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