张 悦1，王献珍2*

1 青海大学研究生院，青海 西宁 2 青海大学附属医院烧伤整形外科，青海 西宁

收稿日期：2022年6月4日；录用日期：2022年6月28日；发布日期：2022年7月5日

摘 要

感染对伤口愈合的影响是多方面的，导致伤口愈合的每个阶段都受到干扰，伤口感染对患者的后果可能包括住院时间延长、心理压力增加、疼痛、甚至会导致脓毒血症的出现，危及患者的生命安全。本文考虑了伤口愈合的四个阶段，概述了感染对伤口愈合的影响。

关键词

伤口感染，愈合阶段，细菌，影响

Stages and Effects of Infection on Wound Healing

Yue Zhang1, Xianzhen Wang2*

1 Graduate School of Qinghai University, Xining Qinghai

2 Burn and Plastic Surgery, The Affiliated Hospital of Qinghai University, Xining Qinghai Received: Jun. 4th, 2022; accepted: Jun. 28th, 2022; published: Jul. 5th, 2022

Abstract

The impact of infection on wound healing is multifaceted, leading to disruption of each stage of wound healing. The consequences of wound infection for patients may include prolonged hospital stay, increased psychological stress, pain, and even the appearance of sepsis, endanger the lives of patients. This article considers the four stages of wound healing and outlines the impact of infection on wound healing.

文章引用: 张悦, 王献珍. 感染对伤口愈合的阶段和影响[J]. 临床医学进展, 2022, 12(7): 6039-6044. DOI: 10.12677/acm.2022.127872

Keywords

Wound Infection, Healing Stage, Bacteria, Impact

Copyright © 2022 by author(s) and Hans Publishers Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/

Lamine Issaga Traore1*, Sidy Sangare1, Gaoussou Sogoba1, Mamaye Kouyate2, Abdoulaye Cisse3, Bakary Skeita4, Sadio Dembele5, Lassina Goita5, Adama Sdiakité6, Mariam Sanogo7, Moussa Camara8, Drissa Traore8

1 Department of General Surgery of the Hospital Fousseyni Daou de Kayes, Kayes, Mali

2 Department of Pediatric Surgery of the Hospital Fousseyni Daou de Kayes, Kayes, Mali

3 Department of Dermatology and Venereology of the Hospital Fousseyni Daou de Kayes, Kayes, Mali

4 Infectious Diseases Unit of the Hospital Fousseyni Daou de Kayes, Kayes, Mali

5 Department of Anesthesia and Intensive Care of the Hospital Fousseyni Daou de Kayes, Kayes, Mali

6 Departmenturology of the Hospital Fousseyni Daou de Kayes, Kayes, Mali

7 Department of Social of the Hospital Fousseyni Daou de Kayes, Kayes, Mali

8 Department of General Surgery of the Hospital CHU du Point “G”, Kayes, Mali

Email:★该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

How to cite this paper: Traore, L.I., Sangare, S., Sogoba, G., Kouyate, M., Cisse, A., Skeita, B., Dembele, S., Goita, L., Sdiakité, A., Sanogo, M., Camara, M. and Traore, D. (2022) Ulcero-Necrotic Wound: Socio-Economic Impact, Kayes, Mali. Surgical Science,13, 280-287. https://doi.org/10.4236/ss.2022.136035

Received: April 13, 2022

Accepted: June 21, 2022

Published: June 24, 2022

Copyright © 2022 by author(s) and Scientific Research Publishing Inc.

This work is licensed under the Creative Commons Attribution International

License (CC BY 4.0).

http://creativecommons.org/licenses/by/4.0/

Abstract

The issue of wound care has always played an important role in the practice of medicine. This is evidenced by Ambroise Paré’s decision to publish his first work on this subject, “La manière de traiter les Plaies” (The Way of Treating Wounds) in 1545.

Objective: To evaluate the therapeutic m ethods we practice and to describe the impact of the pathology on socio-economic and professional development.

Patients and Method: This was a retrospective study carried out at the Fousseyni Daou Hospital in Kayes from January 1, 2018, to December 31, 2020. We included all patients with an ulcero-necrotic wound on immunocompetent terrain hospitalized in the department. Patients with ulcerative necrotic wounds of diabetes, HIV, or cancerous origin were not included. The parameters studied were: etiologies, local care, sequelae, and socio-economic and professional aspects.

Results: We collected 57 patients of whom 43 were men and 14 were women, i.e. a sex ratio of 3. The mean age was 40.7 years with a standard deviation of 8.4 with extremes (7 years and 80 years). The average consultation time was 25.1 days. The most represented socio-professional stratum was agropastoralism in 37 cases (65%). The predominant etiological factor was neglected traumatic wounds in 34 cases (59.6%). The site was the lower limb in 39 cases (68.5%). The germ found was Staphylococcus aureus in 21 cases (36.8%). The particularity during local care was the use of table sugar in 9 cases (15.7%) and maggot therapy in 2 cases (3.5%). Hyperthermia was the clinical sign of aggravation in 22 cases (38.6%) and we diagnosed 2 cases (3.5%) of tetanus. The mortality rate was 15.7% (9 cases) and 30 cases (52.7%) of sequelae after recovery. The average length of hospitalization was 38 days. Hospital care was provided by the social welfare service in 35 cases (61.4%). Nineteen (19) patients (39.5%) were unable to resume their socio-professional activity.

Conclusion: Ulcero-necrotic wounds are complex to manage and can have a lifelong influence on the socio-professional and economic activity of patients.

Keywords

Ulcero-Necrotic Wound, Surgery, Disability, Socio-Economic

Ivan Chorbev, Marija Sotirovska, and Dragan Mihajlov

Faculty of Computer Science and Engineering, Ss. Cyril and Methodius University in Skopje, P.O. BOX 574, 1000 Skopje, Macedonia

Correspondence should be addressed to Ivan Chorbev, 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

Received 31 May 2011; Revised 28 July 2011; Accepted 29 August 2011

Academic Editor: Sotiris A. Pavlopoulos

Copyright © 2011 Ivan Chorbev et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

      Diabetes is classified as the world’s fastest-growing chronic illness that affects millions of people. It is a very serious disease, but the bright side is that it is treatable and can be managed. Proper education in this view is necessary to achieve essential control and prevent the aggregation of this chronic sickness. We have developed a healthcare social network that provides methods for distance learning; opportunities for creation of virtual self-help groups where patients can get information and establish interactions among each other in order to exchange important healthcare-related information; discussion forums; patient-to-healthcare specialist communication. The mission of our virtual community is to increase the independence of people with diabetes, self-management, empower them to take care of themselves, make their everyday activities easier, enrich their medical knowledge, and improve their health condition, make them more productive, and improve their communication with other patients with similar diagnoses. The ultimate goal is to enhance the quality of their life.

Jacquelyn Dawn Parente, Knut Möller

Institute of Technical Medicine, Furtwangen University, Villingen-Schwenningen, Germany

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How to cite this paper: Parente, J.D. and Möller, K. (2017) A Control System Design to Establish Dose-Response Relationships in Wound Healing Therapy. J. Biomedical Science and Engineering, 10, 76-85.

https://doi.org/10.4236/jbise.2017.105B009

Received: April 13, 2017

Accepted: May 3, 2017

Published: May 10, 2017

Abstract

      Advanced biophysical wound healing therapies can apply mechanical, electrical, or light energy to re-stimulate healing processes in chronic wounds. Despite the growing evidence of the clinical efficacy of these therapies, the optimal treatment stimulation parameters remain unknown and there are no standard treatment protocols. We introduce a closed-loop control design as an experimental system to study the dose-response of wound healing therapy treatment within a prescribed multidimensional and multimodal stimulation parameter space. Systems engineering approaches are applied to the control problem for estimation of a transfer function and model equations derived for use in optimal model-based control. The experimental control system design consisted of simultaneous application of biophysical energies inputted into a wound system. A study design set up including the use of negative pressure wound therapy, electrical stimulation therapy, and photobiomodulation device systems was described. Treatment stimulation parameters were selected from experimental ranges used in the scientific literature. Classical control methods and model-based control were suggested for model selection and evaluation and design of the overall control system. An experimental design for multimodal biophysical wound healing therapy control system is introduced to establish the dose-response interactions for development of therapeutic applications and device design.

Keywords

      Chronic wounds, High voltage pulsed current, Low level light therapy, Negative pressure wound therapy, Modeling and control, Photobiomodulation, Wound healing.