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    蔡道章院长

    Custom Mod Mega1

    主任医师、教授、博导,南方医科大学第三附属医院(广东省骨科医院)院长

    • 中德骨科伤口管理学校校长
    • 广东省骨科研究院运动医学研究所所长
    • 广东省内运动医学专业唯一的博士研究生导师
    • 美国哈弗大学医学院骨科访问学者
    • 专业特长处于省内领先、国内或国际先进水平以上
    • 2018年获得“国之名医卓越建树”荣誉称号
    • 2017年被评为全国卫生计生系统先进工作者、广东省医学领军人才
    • 中国医师协会运动医师分会副会长
    • STCOT中国部运动医学分会副主任委员
    • 广东省医学会关节外科分会主任委员
    • 广东省医学会运动医学会分会名誉主任委员
    • 独立承担过国家“863”课题,主持过10余项省、部级科研项目
    • 多份专业杂志编委
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    • Medical nutrition therapy in physiological pregnancy and in pregnancy complicated by obesity and/or diabetes: SID-AMD recommendations 2026-04-08 00:00

      Annunziata Lapolla1  · Maria Grazia Dalfrà1  · Giuseppe Marelli2  · Mario Parrillo3  · Laura Sciacca4  · Maria Angela Sculli5  · Elena Succurro6  · Elisabetta Torlone7  · Ester Vitacolonna8

      Received: 18 September 2024 / Accepted: 27 December 2024 / Published online: 22 January 2025 © Springer-Verlag Italia S.r.l., part of Springer Nature 2025

      Abstract

      Proper nutrition is essential during pregnancy to ensure an adequate supply of nutrients to the foetus and adequate maternal weight gain. In pregnancy complicated by diabetes (both gestational and pre-gestational), diet in terms of both the intake and quality of carbohydrates is an essential factor in glycaemic control. Maternal BMI at conception defines the correct weight increase during gestation in order to reduce maternal-foetal complications related to hypo- or hyper-nutrition. The recommendations presented here, which are based on national and international guidelines and the most recently published data on nutrition in physiological pregnancy and pregnancy complicated by hyperglycaemia and/or obesity, are designed to help healthcare professionals prescribe suitable eating patterns to safeguard the health of the mother and the foetus.

      Communicated by Massimo Federici, M.D.

      Annunziata Lapolla 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

      1 UO Diabetologia, DIMED, Università di Padova, Padova, Italy

      2 Ordine Ospedaliero San Giovanni di Dio Fatebenefratelli, Erba, CO, Italy

      3 UOSD Endocrinologia e Malattie del Ricambio, AO Sant’Anna e San Sebastiano, Caserta, Italy

      4 Dipartimento Medicina Clinica e Sperimentale, Università degli Studi di Catania, Catania, Italy

      5 UOC Diabetologia e Endocrinologia, GOM Bianchi-Melacrino-Morelli, Reggio Calabria, Italy

      6 DPT Scienze Mediche Chirurgiche, Università Magna Grecia, Catanzaro, Italy

      7 AOS Maria della Misericordia SC Endocrinologia e Metabolismo, Università di Perugia, Perugia, Italy

      8 Dipartimento di Medicina e Scienza dell’Invecchiamento, Università di Chieti, Chieti, Italy

    • Exploring metabolomic clues in diabetic retinopathy: a pilot study 2026-04-07 00:00

      Matthew Simonson1  · Yanliang Li2  · J. Jason McAnany2  · Jason C. Park2  · Felix Y. Chau2  · Bharati Prasad3,4 · Silvana Pannain5  · Erin C. Hanlon5  · Eve Van Cauter5  · Kirstie K. Danielson6  · Brian T. Layden6  · Hui Chen7  · George E. Chlipala8  · Carlos Martinez8  · Stephanie J. Crowley9  · Sirimon Reutrakul6

      Received: 23 August 2025 / Accepted: 23 February 2026 © The Author(s) 2026

      Keywords Metabolomics · Diabetic retinopathy · Diabetes Mellitus · Retina

      Communicated by Massimo Federici, M.D Matthew Simonson 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

      1 College of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA

      2 Department of Ophthalmology and Visual Sciences, University of Illinois, Chicago, Chicago, IL, USA

      3 Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA

      4 Jesse Brown Department of Veterans Affairs Hospital, Chicago, IL, USA

      5 Section of Adult and Pediatric Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Chicago, Chicago, IL, USA

      6 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA

      7 Mass Spectrometry Core, Research Resource Center, Office of Vice Chancellor for Research, University of Illinois at Chicago, Chicago, IL, USA

      8 Research Informatics Core, Research Resources Center, University of Illinois at Chicago, Chicago, IL, USA

      9 Biological Rhythms Research Laboratory, Department of Psychiatry & Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA

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Unveiling New Horizons: Advancing Technologies in Cosmeceuticals for Anti-Aging Solutions

Unveiling New Horizons: Advancing Technologies in Cosmeceuticals for Anti-Aging Solutions

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2025-09-22 00:00
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CASIN exerts anti-aging effects through RPL4 on the skin of  naturally aging mice

CASIN exerts anti-aging effects through RPL4 on the skin of naturally aging mice

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2025-09-19 00:00
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Protective, Anti-Inflammatory, and Anti-Aging Effects of Soy Isoflavones on Skin Cells: An Overview of In Vitro and In Vivo Studies

Protective, Anti-Inflammatory, and Anti-Aging Effects of Soy Isoflavones on Skin Cells: An Overview of In Vitro and In Vivo Studies

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2025-09-18 00:00
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Alternative Splicing: Emerging Roles in Anti-Aging Strategies

Alternative Splicing: Emerging Roles in Anti-Aging Strategies

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2025-09-17 00:00
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  • Medical nutrition therapy in physiological pregnancy and in pregnancy complicated by obesity and/or diabetes: SID-AMD recommendations 2026-04-08 00:00

    Annunziata Lapolla1  · Maria Grazia Dalfrà1  · Giuseppe Marelli2  · Mario Parrillo3  · Laura Sciacca4  · Maria Angela Sculli5  · Elena Succurro6  · Elisabetta Torlone7  · Ester Vitacolonna8

    Received: 18 September 2024 / Accepted: 27 December 2024 / Published online: 22 January 2025 © Springer-Verlag Italia S.r.l., part of Springer Nature 2025

    Abstract

    Proper nutrition is essential during pregnancy to ensure an adequate supply of nutrients to the foetus and adequate maternal weight gain. In pregnancy complicated by diabetes (both gestational and pre-gestational), diet in terms of both the intake and quality of carbohydrates is an essential factor in glycaemic control. Maternal BMI at conception defines the correct weight increase during gestation in order to reduce maternal-foetal complications related to hypo- or hyper-nutrition. The recommendations presented here, which are based on national and international guidelines and the most recently published data on nutrition in physiological pregnancy and pregnancy complicated by hyperglycaemia and/or obesity, are designed to help healthcare professionals prescribe suitable eating patterns to safeguard the health of the mother and the foetus.

    Communicated by Massimo Federici, M.D.

    Annunziata Lapolla 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

    1 UO Diabetologia, DIMED, Università di Padova, Padova, Italy

    2 Ordine Ospedaliero San Giovanni di Dio Fatebenefratelli, Erba, CO, Italy

    3 UOSD Endocrinologia e Malattie del Ricambio, AO Sant’Anna e San Sebastiano, Caserta, Italy

    4 Dipartimento Medicina Clinica e Sperimentale, Università degli Studi di Catania, Catania, Italy

    5 UOC Diabetologia e Endocrinologia, GOM Bianchi-Melacrino-Morelli, Reggio Calabria, Italy

    6 DPT Scienze Mediche Chirurgiche, Università Magna Grecia, Catanzaro, Italy

    7 AOS Maria della Misericordia SC Endocrinologia e Metabolismo, Università di Perugia, Perugia, Italy

    8 Dipartimento di Medicina e Scienza dell’Invecchiamento, Università di Chieti, Chieti, Italy

  • Exploring metabolomic clues in diabetic retinopathy: a pilot study 2026-04-07 00:00

    Matthew Simonson1  · Yanliang Li2  · J. Jason McAnany2  · Jason C. Park2  · Felix Y. Chau2  · Bharati Prasad3,4 · Silvana Pannain5  · Erin C. Hanlon5  · Eve Van Cauter5  · Kirstie K. Danielson6  · Brian T. Layden6  · Hui Chen7  · George E. Chlipala8  · Carlos Martinez8  · Stephanie J. Crowley9  · Sirimon Reutrakul6

    Received: 23 August 2025 / Accepted: 23 February 2026 © The Author(s) 2026

    Keywords Metabolomics · Diabetic retinopathy · Diabetes Mellitus · Retina

    Communicated by Massimo Federici, M.D Matthew Simonson 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

    1 College of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA

    2 Department of Ophthalmology and Visual Sciences, University of Illinois, Chicago, Chicago, IL, USA

    3 Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA

    4 Jesse Brown Department of Veterans Affairs Hospital, Chicago, IL, USA

    5 Section of Adult and Pediatric Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Chicago, Chicago, IL, USA

    6 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA

    7 Mass Spectrometry Core, Research Resource Center, Office of Vice Chancellor for Research, University of Illinois at Chicago, Chicago, IL, USA

    8 Research Informatics Core, Research Resources Center, University of Illinois at Chicago, Chicago, IL, USA

    9 Biological Rhythms Research Laboratory, Department of Psychiatry & Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA

  • The close relationship between inflammation and insulin resistance: a comparative perspective from a new angle 2026-04-04 00:00

    Xiaoyan Wang1  · Run Yang1  · Jingxiang Li1  · Yongqi Liang2  · Chenxi Jin1  · Yining Xu1  · Xianbo Wu2  · Mengchen Zou1

    Received: 4 July 2025 / Accepted: 30 September 2025 / Published online: 15 October 2025 © The Author(s) 2025

    Abstract

        Background Excess weight is a progressive metabolic epidemic, and inflammation plays an important role in the progres-sion of disease. Insulin resistance (IR) is an important feature of obesity, but it does not reflect systemic inflammation. Cur-rently, there is a lack of effective clinical tools for early risk stratification and intervention in physically active people.

        Methods This was a prospective cohort of 72,262 overweight but physically active persons in the UK Biobank. The TyG was combined with hsCRP, waist circumference (WC), or body mass index (BMI) as indices of IR. Adjusted Cox regression, interaction tests, restricted cubic splines (RCS) analysis, Kaplan-Meier analysis, and Harrell’s C-index were used to examine the relations and time-dependent predictive power.

        Results During 12.7 years of follow-up, 1,477 participants developed metabolic dysfunction-associated fatty liver disease (MAFLD). RCS analysis suggested TyG-hsCRP had a nonlinear positive correlations with all-cause mortality. Compared to the lowest quartile group, the corrected hazard ratio (HR) (95% confidence interval [CI]) of new-onset MAFLD in maximum quartile groups for TyG-hsCRP was 1.94(1.62–2.32), for TyG-WC was 1.78(1.44–2.18), for TyG-BMI was 1.36(1.12–1.65), and for TyG was 1.41(1.15–1.72). The relation between C-index of TyG-hsCRP and MAFLD was higher than that of other TyG indices. Similar results were observed in all-cause mortality.

        Conclusion TyG-hsCRP is superior to other indices for identifying risk of MAFLD and all-cause mortality in overweight but physically active people. Our findings suggest the importance of inflammatory metabolism and provide evidence for effectively early anti-inflammatory treatments.

        Keywords Excess weight · Inflammation · Insulin resistance · Physically active

    Communicated by Salvatore Corrao, M.D

        Mengchen Zou

        该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

        Xianbo Wu

        该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

    1 Department of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University, 1838 Guangzhou Road North, Guangzhou 510515, China

    2 Department of Occupational Health and Medicine, School of Public Health, Southern Medical University, Guangzhou, China

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