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【指南与共识】2025版《中国糖尿病足防治实践指南》解读 2026-05-30 00:00

原创邓呈亮中华医学美学美容杂志

2026年4月2日 20:00 河北 5人

版权归中华医学会所有。

未经授权，不得转载、摘编本刊文章。

引用本文：简喜超, 简扬, 邓呈亮. 2025版《中国糖尿病足防治实践指南》解读[J]. 中华医学美学美容杂志, 2026, 32(2): 99-103. DOI: 10.3760/cma.j.cn114657-20251215-00266.

通信作者：邓呈亮，Email：该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。
Automated insulin delivery in pregnant women with type 1 diabetes mellitus: a systematic review and meta-analysis 2026-05-30 00:00

Athina Stamati1 · Athanasios Christoforidis2

Received: 7 October 2024 / Accepted: 31 December 2024 / Published online: 10 January 2025 © The Author(s) 2025

Abstract

Aims To assess the efficacy and safety of automated insulin delivery (AID) systems compared to standard care in managing glycaemic control during pregnancy in women with Type 1 Diabetes Mellitus (T1DM).

Methods We searched MEDLINE, Cochrane Library, registries and conference abstracts up to June 2024 for randomized controlled trials (RCTs) and observational studies comparing AID to standard care in pregnant women with T1DM. We con-ducted random effects meta-analyses for % of 24-h time in range of 63–140 mg/dL (TIR), time in hyperglycaemia (>140 mg/ dl and>180 mg/dL), hypoglycaemia (<63 mg/dl and<54 mg/dL), total insulin dose (units/kg/day), glycemic variability (%), changes in HbA1c (%), maternal and fetal outcomes.

Results Thirteen studies (450 participants) were included. AID significantly increased TIR (Mean difference, MD 7.01%, 95% CI 3.72–10.30) and reduced time in hyperglycaemia>140 mg/dL and>180 mg/dL (MD – 5.09%, 95% CI – 9.41 to – 0.78 and MD – 2.44%, 95% CI – 4.69 to – 0.20, respectively). Additionally, glycaemic variability was significantly reduced (MD – 1.66%, 95% CI – 2.73 to – 0.58). Other outcomes did not differ significantly.

Conclusion AID systems effectively improve glycaemic control during pregnancy in women with T1DM by increasing TIR and reducing hyperglycaemia without any observed adverse short-term effects on maternal and fetal outcomes.

Keywords Automated insulin delivery · Pregnancy · Type 1 diabetes mellitus · Systematic review · Meta-analysis
A nationwide registry-based cohort study of the association between childhood dental caries and gingivitis with type 2 diabetes in adulthood 2026-05-29 00:00

Nikoline Nygaard1 · Anne Kirstine Eriksen2 · Lars Ängquist3 · Daniel Belstrøm1 · Evelina Stankevic3 · Torben Hansen3 · Anja Olsen2 · Merete Markvart1

Received: 15 August 2024 / Accepted: 22 December 2024 / Published online: 13 January 2025 © The Author(s) 2025

Abstract

Background Evidence suggests a bidirectional relationship between oral health status and type 2 diabetes (T2D) in adults. Studies on associations between childhood oral health and T2D in adulthood are lacking.

Methods This is a nationwide Danish registry-based cohort study of individuals born between 1963 and 1972, having at least one registration in the National Child Odontology Registry between 1972 and 1987 (n=627,758). Follow-up lasted from 1995 to 2018. Main exposure variables were the highest achieved levels of dental caries and gingivitis between 1972 and 1987. The outcome was T2D diagnosis during follow-up. Data was analyzed using Cox-regression, stratified on sex, with age as the underlying timescale and highest achieved level of education between age 25–30 years as Cox-strata. Main analyses were conducted with and without age-restrictions (T2D diagnosis before/after age 40).

Results Compared to lowest-level references, high levels of gingivitis associated with increased hazard ratios (HRs) of T2D in both males (HR [95% confidence interval]: 1.59 [1.47; 1.72]) and females (1.87 [1.68; 2.08]), as did severe dental caries (males: (1.15 [1.04; 1.27], in females: 1.19 [1.06; 1.35]). Below age 40, gingivitis associated with increased HRs in males (1.84 ([1.58; 2.15]) and females (1.94 [1.63; 2.30]). Above age 40, both exposures displayed higher HRs in males (high gin-givitis: 1.52 [1.39; 1.66] vs. severe caries: 1.23 [1.09; 1.38]) and females (1.83 [1.59; 2.10] vs. 1.37 [1.17; 1.59]).

Conclusions Data suggest an association between childhood dental caries and gingivitis with risk of receiving a T2D diag-nosis in adulthood. However, results are affected by residual confounding warranting further studies.

Keywords Cohort studies · Dental caries · Diabetes mellitus · Type 2 · Gingivitis

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主任医师、教授、博导，南方医科大学第三附属医院（广东省骨科医院）院长

原创邓呈亮中华医学美学美容杂志

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Custom Mod Mega1

主任医师、教授、博导，南方医科大学第三附属医院（广东省骨科医院）院长

原创 邓呈亮 中华医学美学美容杂志

文献精选

易漏诊致命的颈部脓肿病因，可能与进化论有关！

一招，避免伤口问题给主任抹黑

有一类疾病，护士比医生更专业！

户外伤口自救：卫生巾好过涂抹各种粉末百倍！

原创 邓呈亮 中华医学美学美容杂志

消息订阅

学术会议

伤口世界提示

原创邓呈亮中华医学美学美容杂志

原创邓呈亮中华医学美学美容杂志